Department of Orthopaedics and Traumatology, Turku University Hospital, PO Box 52, 20521, Turku, Finland.
University of Turku, Turku, Finland.
Eur Spine J. 2021 Sep;30(9):2413-2426. doi: 10.1007/s00586-021-06827-y. Epub 2021 Apr 12.
Positive spinal sagittal alignment is known to correlate with pain and disability. The association between lumbar spinal stenosis and spinal sagittal alignment is less known, as is the effect of lumbar decompressive surgery on the change in that alignment. The objective was to study the evidence on the effect of lumbar decompressive surgery on sagittal spinopelvic alignment.
The Cochrane Controlled Trials Register (CENTRAL), Medline, Embase, Scopus and Web of Science databases were searched in October 2019, unrestricted by date of publication. The study selection was performed by two independent reviewers. The risk of systematic bias was assessed according to the NIH Quality Assessment Tool. The data were extracted using a pre-defined standardized form.
The search resulted in 807 records. Of these, 18 were considered relevant for the qualitative analysis and 15 for the meta-synthesis. The sample size varied from 21 to 89 and the average age was around 70 years. Decompression was mostly performed on one or two levels and the surgical techniques varied widely. The pooled effect sizes were most statistically significant but small. For lumbar lordosis, the effect size was 3.0 (95% CI 2.2 to 3.7) degrees. Respectively, for pelvic tilt and sagittal vertical axis, the effect sizes were - 1.6 (95% CI .2.6 to - 0.5) degrees and - 9.6 (95% CI - 16.0 to - 3.3) mm.
It appears that decompression may have a small, statistically significant but probably clinically insignificant effect on lumbar lordosis, sagittal vertical axis and pelvic tilt.
已知阳性脊柱矢状位排列与疼痛和残疾相关。腰椎管狭窄症与脊柱矢状位排列的相关性知之甚少,腰椎减压手术对该排列变化的影响也是如此。本研究旨在研究腰椎减压手术对脊柱矢状位骨盆排列的影响的证据。
2019 年 10 月,检索了 Cochrane 对照试验注册库(CENTRAL)、Medline、Embase、Scopus 和 Web of Science 数据库,未对出版日期进行限制。由两名独立评审员进行研究选择。根据 NIH 质量评估工具评估系统偏倚风险。使用预先定义的标准化表格提取数据。
检索结果产生了 807 条记录。其中,有 18 条被认为与定性分析相关,15 条与荟萃合成相关。样本量从 21 到 89 不等,平均年龄约为 70 岁。减压主要在一个或两个节段进行,手术技术差异很大。汇总的效应量在统计学上最为显著,但幅度较小。对于腰椎前凸,效应量为 3.0(95%置信区间 2.2 至 3.7)度。分别为骨盆倾斜和矢状垂直轴,效应量为-1.6(95%置信区间 0.2 至-0.5)度和-9.6(95%置信区间-16.0 至-3.3)mm。
似乎减压术对腰椎前凸、矢状垂直轴和骨盆倾斜可能有小的、统计学上显著但可能临床上无意义的影响。