正常人体小肠中的癌胚抗原（CEA）：光镜和电镜研究

Isaacson P, Judd M A

Gut. 1977 Oct;18(10):786-91. doi: 10.1136/gut.18.10.786.

An immunoperoxidase method for the demonstration of carcinoembryonic antigen (CEA) in tissues was applied to formalin-fixed paraffin embedded and glutaraldehyde-fixed resin sections of normal human small intestine. CEA could easily be demonstrated coating the surface of the small intestine, lining the crypts, and in goblet cells, indicating its presence there in considerable concentration. At the ultrastructural level CEA was localised in the glycocalyx and in mucin granules of goblet cells but not intracytoplasmically.

一种用于在组织中显示癌胚抗原（CEA）的免疫过氧化物酶方法应用于正常人小肠的福尔马林固定石蜡包埋和戊二醛固定树脂切片。可以很容易地证明CEA覆盖在小肠表面、隐窝内衬以及杯状细胞中，表明其在那里有相当高的浓度。在超微结构水平上，CEA定位于糖萼和杯状细胞的粘蛋白颗粒中，而不是在细胞质内。