腮腺癌中癌胚抗原（CEA）的免疫组织化学检测。52例病例分析。
Immunohistochemical detection of carcinoembryonic antigen (CEA) in parotid gland carcinomas. Analysis of 52 cases.
作者信息
Caselitz J, Jaup T, Seifert G
出版信息
Virchows Arch A Pathol Anat Histol. 1981;394(1-2):49-60. doi: 10.1007/BF00431664.
PMID:6278701
Abstract
The presence of CEA in parotid gland tumours was studied by immunohistochemical methods. 52 cases were analysed. 7 of 8 adenocarcinomas, 3 of 5 cystadenocarcinomas, 3 of 4 adenoid cystic carcinomas and all 3 salivary duct carcinomas were positive for CEA. 5 of 8 squamous cell carcinomas and 9 of 21 carcinomas in a pleomorphic adenoma were also positive for CEA. The anaplastic carcinomas were negative. The distribution pattern of the presence of CEA in the carcinomatous and the adjacent normal or inflamed tissue was analysed. The results are discussed with regard to their histogenetic and diagnostic implications.
摘要
采用免疫组化方法研究了腮腺肿瘤中癌胚抗原（CEA）的存在情况。分析了52例病例。8例腺癌中有7例、5例囊腺癌中有3例、4例腺样囊性癌中有3例以及所有3例涎腺导管癌CEA呈阳性。8例鳞状细胞癌中有5例以及21例多形性腺瘤中的癌中有9例CEA也呈阳性。间变性癌呈阴性。分析了癌组织及相邻正常或炎症组织中CEA存在的分布模式。并就其组织发生学及诊断意义对结果进行了讨论。
相似文献
1
Immunohistochemical detection of carcinoembryonic antigen (CEA) in parotid gland carcinomas. Analysis of 52 cases.腮腺癌中癌胚抗原（CEA）的免疫组织化学检测。52例病例分析。
Virchows Arch A Pathol Anat Histol. 1981;394(1-2):49-60. doi: 10.1007/BF00431664.
2
Detection of tissue polypeptide antigen in salivary glands and salivary gland tumors. An immunohistochemical study.
Appl Pathol. 1983;1(2):115-20.
3
Histological and immunocytochemical examinations of the stromal reaction in carcinomas of the parotid gland. Analysis of 52 cases.腮腺癌间质反应的组织学和免疫细胞化学检查。52例分析。
J Cancer Res Clin Oncol. 1980;96(2):193-209. doi: 10.1007/BF00405504.
4
Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue.腮腺癌中的乳铁蛋白和溶菌酶。与正常及炎症组织中出现情况的比较免疫细胞化学研究。
Virchows Arch A Pathol Anat Histol. 1981;394(1-2):61-73. doi: 10.1007/BF00431665.
5
Tumor antigens in neoplasms of the human parotid gland.人类腮腺肿瘤中的肿瘤抗原。
J Oral Pathol. 1982;11(5):374-86. doi: 10.1111/j.1600-0714.1982.tb00179.x.
6
Presence of carcinoembryonic antigen (CEA) in the normal and inflamed human parotid gland. An immunohistochemical study of 31 cases.正常及炎症状态下人腮腺中癌胚抗原（CEA）的存在：31例免疫组织化学研究
J Cancer Res Clin Oncol. 1981;100(2):205-11. doi: 10.1007/BF00403366.
7
Immunohistochemical localization of carcinoembryonic antigen in carcinoma in pleomorphic adenoma of salivary gland: use in the diagnosis of benign and malignant lesions.癌胚抗原在涎腺多形性腺瘤癌变中的免疫组化定位：用于良恶性病变的诊断
Tohoku J Exp Med. 1986 Jul;149(3):329-40. doi: 10.1620/tjem.149.329.
8
[Immunohistochemical study of carcinoembryonic antigen (CEA) in minor salivary gland tumors].
Kokubyo Gakkai Zasshi. 1984 Jun;51(2):217-37.
9
[Antibodies against intermediate filaments--a contribution to the differential diagnosis of salivary gland tumors].[抗中间丝抗体——对涎腺肿瘤鉴别诊断的贡献]
Laryngol Rhinol Otol (Stuttg). 1986 Jul;65(7):384-8.
10
Immunohistochemical localization of carcinoembryonic antigen (CEA) in salivary gland tumors.
Oral Surg Oral Med Oral Pathol. 1990 Apr;69(4):479-82. doi: 10.1016/0030-4220(90)90382-3.
引用本文的文献
1
Adenoid cystic carcinoma: An unusual presentation.腺样囊性癌：一种不寻常的表现。
J Oral Maxillofac Pathol. 2014 May;18(2):286-90. doi: 10.4103/0973-029X.140796.
2
Human prominin-1 (CD133) is detected in both neoplastic and non-neoplastic salivary gland diseases and released into saliva in a ubiquitinated form.在肿瘤性和非肿瘤性唾液腺疾病中均检测到人类促红细胞生成素-1（CD133），且其以泛素化形式释放到唾液中。
PLoS One. 2014 Jun 9;9(6):e98927. doi: 10.1371/journal.pone.0098927. eCollection 2014.
3
The embryonal carcinoma of the parotid gland. A rare example of an embryonal tumor.腮腺胚胎性癌。一种罕见的胚胎性肿瘤实例。
Virchows Arch A Pathol Anat Histopathol. 1984;403(4):425-40. doi: 10.1007/BF00737291.
4
Immunofluorescence study of secretory epithelial markers in pleomorphic adenomas.多形性腺瘤中分泌性上皮标志物的免疫荧光研究。
Virchows Arch A Pathol Anat Histopathol. 1984;403(3):291-300. doi: 10.1007/BF00694905.
5
Lactoferrin and lysozyme in carcinomas of the parotid gland. A comparative immunocytochemical study with the occurrence in normal and inflamed tissue.腮腺癌中的乳铁蛋白和溶菌酶。与正常及炎症组织中出现情况的比较免疫细胞化学研究。
Virchows Arch A Pathol Anat Histol. 1981;394(1-2):61-73. doi: 10.1007/BF00431665.
6
Glycoprotein tumour markers in head and neck neoplasms--a consecutive study on CA-50, CA 19-9, and CEA.头颈部肿瘤中的糖蛋白肿瘤标志物——关于CA-50、CA 19-9和癌胚抗原的连续性研究
J Cancer Res Clin Oncol. 1988;114(4):394-8. doi: 10.1007/BF02128184.
7
Multiple expression of tissue markers in mucoepidermoid carcinomas and acinic cell carcinomas of the salivary glands.涎腺黏液表皮样癌和腺泡细胞癌中组织标志物的多重表达。
Virchows Arch A Pathol Anat Histopathol. 1989;414(5):407-13. doi: 10.1007/BF00718624.
8
The pleomorphic adenoma of salivary glands transplanted on athmymic mice. A lightmicroscopical and immunohistochemical investigation.移植于无胸腺小鼠的涎腺多形性腺瘤。光镜及免疫组化研究。
Virchows Arch A Pathol Anat Histopathol. 1985;408(2-3):191-209. doi: 10.1007/BF00707982.
本文引用的文献
1
DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.通过免疫耐受和吸收技术证明人类结肠癌中的肿瘤特异性抗原
J Exp Med. 1965 Mar 1;121(3):439-62. doi: 10.1084/jem.121.3.439.
2
Salivary carcinoembryonic antigen (CEA) in cystic fibrosis.囊性纤维化患者的唾液癌胚抗原（CEA）
Pediatr Res. 1980 Mar;14(3):187-9. doi: 10.1203/00006450-198003000-00002.
3
Presence of carcinoembryonic antigen (CEA) in the normal and inflamed human parotid gland. An immunohistochemical study of 31 cases.正常及炎症状态下人腮腺中癌胚抗原（CEA）的存在：31例免疫组织化学研究
J Cancer Res Clin Oncol. 1981;100(2):205-11. doi: 10.1007/BF00403366.
4
Histological and immunocytochemical examinations of the stromal reaction in carcinomas of the parotid gland. Analysis of 52 cases.腮腺癌间质反应的组织学和免疫细胞化学检查。52例分析。
J Cancer Res Clin Oncol. 1980;96(2):193-209. doi: 10.1007/BF00405504.
5
Identification of carcinoembryonic antigen in the C-cell of the normal thyroid.正常甲状腺C细胞中癌胚抗原的鉴定。
Cancer. 1980 Jan 1;45(1):98-101. doi: 10.1002/1097-0142(19800101)45:1<98::aid-cncr2820450117>3.0.co;2-c.
6
Carcinoembryonic antigen assay in cancer of the colon and pancreas and other digestive tract disorders.癌胚抗原检测在结肠癌、胰腺癌及其他消化道疾病中的应用
Am J Dig Dis. 1971 Jan;16(1):1-7. doi: 10.1007/BF02233781.
7
[Cellular localization of an embryonic antigen in human colonic tumors].[一种胚胎抗原在人结肠肿瘤中的细胞定位]
Int J Cancer. 1969 Nov 15;4(6):874-9. doi: 10.1002/ijc.2910040616.
8
Demonstration of an antigen common to several varieties of neoplasia.几种肿瘤共同抗原的证实。
N Engl J Med. 1971 Jul 15;285(3):138-41. doi: 10.1056/NEJM197107152850302.
9
Carcinoembryonic antigen (CEA) assay. A laboratory adjunct in the diagnosis and management of cancer.癌胚抗原（CEA）检测：癌症诊断与管理中的一项实验室辅助手段。
Hum Pathol. 1974 Mar;5(2):139-47. doi: 10.1016/s0046-8177(74)80061-4.
Zotero 插件