Barahona Z Daniela, Adlerstein L Isabel, Faure R María Ignacia
Departamento de Imagenología, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile.
Rev Med Chil. 2020 Oct;148(10):1504-1507. doi: 10.4067/S0034-98872020001001504.
The use of positron emission tomography with computed tomography (PET/CT) for adult cancer patients is widespread, however, its use in pediatric patients is limited by fear of radiation, monetary cost and lack of awareness of its greater sensitivity in the evaluation of some types of tumors. Ewing's sarcoma is one of the primary pediatric malignancies in which PET/CT with 18F-labeled fluorodeoxyglucose (18F-FDG) has demonstrated greater sensitivity in the evaluation of bone metastases compared to scintigraphy, as well as in the evaluation of treatment response. We report a 13 years old female consulting for retrosternal pain. A chest CT scan showed an infiltrating mass originating in the sternum. A biopsy confirmed the presence of an Ewing sarcoma. The tumor was staged with PET/CT which showed multiple bone lesions not visible in previous studies.
正电子发射断层扫描与计算机断层扫描(PET/CT)在成年癌症患者中的应用十分广泛,然而,由于担心辐射、费用以及对其在某些类型肿瘤评估中更高敏感性的认识不足,其在儿科患者中的应用受到限制。尤因肉瘤是主要的儿科恶性肿瘤之一,在评估骨转移方面,与骨闪烁显像相比,18F标记的氟脱氧葡萄糖(18F-FDG)PET/CT已显示出更高的敏感性,在评估治疗反应方面也是如此。我们报告一名13岁女性因胸骨后疼痛前来咨询。胸部CT扫描显示一个起源于胸骨的浸润性肿块。活检证实为尤因肉瘤。通过PET/CT对肿瘤进行分期,结果显示出多个先前检查未发现的骨病变。