Zachman R D
Perinatal Center, University of Wisconsin.
Int J Vitam Nutr Res. 1988;58(1):17-21.
Newborn rabbit littermates were divided randomly and placed in environments of 21% oxygen or 70-75% oxygen for 68 hours. At that time lungs and liver were removed, and retinoids were measured by HPLC with methanol as the mobile phase. Lungs exposed to 70-75% oxygen had less retinol than controls, and livers of oxygen exposed animals had less retinyl palmitate and retinyl stearate than control animals. This effect of oxygen on newborn lung and liver retinol stores has not previously been reported.
新生兔同窝仔随机分组，置于含21%氧气或70 - 75%氧气的环境中68小时。届时取出肺和肝脏，以甲醇为流动相，用高效液相色谱法测定类视黄醇。暴露于70 - 75%氧气环境中的肺组织视黄醇含量低于对照组，暴露于该氧气环境的动物肝脏中棕榈酸视黄酯和硬脂酸视黄酯含量低于对照动物。此前尚未报道过氧气对新生兔肺和肝脏视黄醇储备的这种影响。
