Department of Paediatrics, Launceston General Hospital, Launceston, Tasmania, Australia.
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.
J Paediatr Child Health. 2021 Sep;57(9):1397-1401. doi: 10.1111/jpc.15473. Epub 2021 Apr 13.
To describe the epidemiology of invasive Salmonella disease in children in the Northern Territory, Australia.
Design: A retrospective review of invasive salmonellosis cases identified by pathology records and the Northern Territory Notifiable Disease Surveillance System. Case definitions: Those aged 18 years or under, with Salmonella cultured from a usually sterile site, collected in the Northern Territory between 1 July 2005 and 30 June 2015.
The primary outcome measure was the annual incidence rate of invasive salmonellosis, comparing rates between Indigenous and non-Indigenous children.
There were 86 cases of invasive Salmonella infection in children over the 10-year period; an annual incidence of 14.1 per 100 000 population, in those aged less than 18 years. Gastrointestinal Salmonella notifications were similar between Indigenous and non-Indigenous children. In children aged less than 15 years, the rate of invasive salmonellosis was higher in Indigenous children compared to non-Indigenous children (23.4 per 100 000 compared with 11.6 per 100 000); rate ratio 2.0 (95% confidence interval 1.3-3.3, P = 0.002). Indigenous children with invasive salmonellosis had a median hospital stay of 8 days, which was compared to 5 days for non-Indigenous children (P = 0.015). The highest incidence rate of invasive salmonellosis occurred in Indigenous patients less than 12 months of age (138 per 100 000).
The Northern Territory of Australia has high rates of invasive salmonellosis in children. Indigenous and non-Indigenous children experience similar rates of Salmonella gastroenteritis but Indigenous children experience higher rates of invasive salmonellosis.
描述澳大利亚北部地区儿童侵袭性沙门氏菌病的流行病学情况。
设计：通过病理记录和北领地传染病监测系统回顾性分析侵袭性沙门氏菌病病例。病例定义：年龄在 18 岁或以下，从通常无菌部位培养出沙门氏菌，2005 年 7 月 1 日至 2015 年 6 月 30 日在北领地采集。
主要结局指标是侵袭性沙门氏菌病的年发病率，比较土著儿童和非土著儿童的发病率。
在 10 年期间，共有 86 例儿童侵袭性沙门氏菌感染；18 岁以下儿童的发病率为每 10 万人 14.1 例。土著儿童和非土著儿童的胃肠道沙门氏菌报告数相似。在年龄小于 15 岁的儿童中，土著儿童侵袭性沙门氏菌病的发病率高于非土著儿童（每 10 万人 23.4 例比 11.6 例）；发病率比为 2.0（95%置信区间 1.3-3.3，P=0.002）。患有侵袭性沙门氏菌病的土著儿童的中位住院时间为 8 天，而非土著儿童为 5 天（P=0.015）。侵袭性沙门氏菌病发病率最高的是年龄在 12 个月以下的土著患者（每 10 万人 138 例）。
澳大利亚北部地区儿童侵袭性沙门氏菌病发病率较高。土著儿童和非土著儿童患沙门氏菌肠胃炎的发病率相似，但土著儿童患侵袭性沙门氏菌病的发病率较高。
