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肺转移性下颌骨造釉细胞瘤:罕见病例报告。

Metastatic mandibular ameloblastoma of the lung ten years after primary resection: A rare case report.

机构信息

Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust, London.

Department of Histopathology, University College London Hospitals NHS Foundation Trust, London.

出版信息

Monaldi Arch Chest Dis. 2021 Apr 9;91(2). doi: 10.4081/monaldi.2021.1643.

Abstract

Ameloblastoma is a rare odontogenic neoplasm of the jaw. It usually behaves as a benign, slow growing tumour of the oral cavity with a high recurrence rate, especially when it is inadequately resected. A small proportion of ameloblastomas metastasize to distant organs, with lungs representing the most common site of metastatic spread. In this report, we present the case of a middle-aged man with two pulmonary nodules and a history of mandibular ameloblastoma excised 10 years prior to this radiological finding. Following resection and histopathological analysis of the lung lesion, a diagnosis of metastatic ameloblastoma was confirmed. No local recurrence of the primary tumour was identified. At 1-year follow-up, the patient had no evidence of local or metastatic disease.

摘要

成釉细胞瘤是一种罕见的颌骨牙源性肿瘤。它通常表现为口腔内良性、生长缓慢的肿瘤,复发率高,尤其是当切除不充分时。一小部分成釉细胞瘤会转移到远处器官,肺部是最常见的转移部位。在本报告中,我们介绍了一名中年男性的病例,他有两个肺结节,且在该影像学发现前 10 年曾切除下颌成釉细胞瘤。肺部病变切除并进行组织病理学分析后,确诊为转移性成釉细胞瘤。未发现原发性肿瘤局部复发。在 1 年的随访中,患者无局部或转移性疾病的证据。

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