Department of Thoracic Surgery, University College London Hospitals NHS Foundation Trust, London.
Department of Histopathology, University College London Hospitals NHS Foundation Trust, London.
Monaldi Arch Chest Dis. 2021 Apr 9;91(2). doi: 10.4081/monaldi.2021.1643.
Ameloblastoma is a rare odontogenic neoplasm of the jaw. It usually behaves as a benign, slow growing tumour of the oral cavity with a high recurrence rate, especially when it is inadequately resected. A small proportion of ameloblastomas metastasize to distant organs, with lungs representing the most common site of metastatic spread. In this report, we present the case of a middle-aged man with two pulmonary nodules and a history of mandibular ameloblastoma excised 10 years prior to this radiological finding. Following resection and histopathological analysis of the lung lesion, a diagnosis of metastatic ameloblastoma was confirmed. No local recurrence of the primary tumour was identified. At 1-year follow-up, the patient had no evidence of local or metastatic disease.
成釉细胞瘤是一种罕见的颌骨牙源性肿瘤。它通常表现为口腔内良性、生长缓慢的肿瘤,复发率高,尤其是当切除不充分时。一小部分成釉细胞瘤会转移到远处器官,肺部是最常见的转移部位。在本报告中,我们介绍了一名中年男性的病例,他有两个肺结节,且在该影像学发现前 10 年曾切除下颌成釉细胞瘤。肺部病变切除并进行组织病理学分析后,确诊为转移性成釉细胞瘤。未发现原发性肿瘤局部复发。在 1 年的随访中,患者无局部或转移性疾病的证据。