Isenberg Sarina R, Meaney Christopher, May Peter, Tanuseputro Peter, Quinn Kieran, Qureshi Danial, Saunders Stephanie, Webber Colleen, Seow Hsien, Downar James, Smith Thomas J, Husain Amna, Lawlor Peter G, Fowler Rob, Lachance Julie, McGrail Kimberlyn, Hsu Amy T
Bruyère Research Institute, 43 Bruyère St, Office 264J-G, Ottawa, ON, K1N 5C8, Canada.
Department of Family and Community Medicine, University of Toronto, Toronto, Canada.
BMC Health Serv Res. 2021 Apr 13;21(1):331. doi: 10.1186/s12913-021-06335-1.
Inpatient palliative care is associated with lower inpatient costs; however, this has yet to be studied using a more nuanced, multi-tiered measure of inpatient palliative care and a national population-representative dataset. Using a population-based cohort of Canadians who died in hospital, our objectives were to: describe patients' receipt of palliative care and active interventions in their terminal hospitalization; and examine the relationship between inpatient palliative care and hospitalization costs.
Retrospective cohort study using data from the Discharge Abstract Database in Canada between fiscal years 2012 and 2015. The cohort were Canadian adults (age ≥ 18 years) who died in hospital between April 1st, 2012 and March 31st, 2015 (N = 250,640). The exposure was level of palliative care involvement defined as: medium-high, low, or no palliative care. The main measure was acute care costs calculated using resource intensity weights multiplied by the cost of standard hospital stay, represented in 2014 Canadian dollars (CAD). Descriptive statistics were represented as median (IQR), and n(%). We modelled cost as a function of palliative care using a gamma generalized estimating equation (GEE) model, accounting for clustering by hospital.
There were 250,640 adults who died in hospital. Mean age was 76 (SD 14), 47% were female. The most common comorbidities were: metastatic cancer (21%), heart failure (21%), and chronic obstructive pulmonary disease (16%). Of the decedents, 95,450 (38%) had no palliative care involvement, 98,849 (38%) received low involvement, and 60,341 (24%) received medium to high involvement. Controlling for age, sex, province and predicted hospital mortality risk at admission, the cost per day of a terminal hospitalization was: $1359 (95% CI 1323: 1397) (no involvement), $1175 (95% CI 1146: 1206) (low involvement), and $744 (95% CI 728: 760) (medium-high involvement).
Increased involvement of palliative care was associated with lower costs. Future research should explore whether this relationship holds for non-terminal hospitalizations, and whether palliative care in other settings impacts inpatient costs.
住院姑息治疗与较低的住院费用相关;然而,尚未使用更细致入微的、多层次的住院姑息治疗衡量标准以及全国人口代表性数据集对此进行研究。利用以加拿大在医院死亡的人群为基础的队列,我们的目标是:描述患者在临终住院期间接受姑息治疗和积极干预的情况;并研究住院姑息治疗与住院费用之间的关系。
采用回顾性队列研究,使用2012财年至2015财年加拿大出院摘要数据库中的数据。队列是2012年4月1日至2015年3月31日期间在医院死亡的加拿大成年人(年龄≥18岁)(N = 250,640)。暴露因素是姑息治疗参与程度,定义为:中高、低或无姑息治疗。主要衡量指标是急性护理费用,使用资源强度权重乘以标准住院天数的费用来计算,以2014年加拿大元(CAD)表示。描述性统计以中位数(四分位间距)和n(%)表示。我们使用伽马广义估计方程(GEE)模型将费用建模为姑息治疗的函数,同时考虑医院聚类情况。
有250,640名成年人在医院死亡。平均年龄为76岁(标准差14),47%为女性。最常见的合并症为:转移性癌症(21%)、心力衰竭(21%)和慢性阻塞性肺疾病(16%)。在死者中,95,450人(38%)未接受姑息治疗,98,849人(38%)接受低程度姑息治疗,60,341人(24%)接受中高程度姑息治疗。在控制年龄、性别、省份和入院时预测的医院死亡风险后,临终住院每天的费用为:1359加元(95%置信区间1323:1397)(未接受姑息治疗)、1175加元(95%置信区间1146:1206)(低程度姑息治疗)和744加元(95%置信区间728:760)(中高程度姑息治疗)。
姑息治疗参与程度的提高与费用降低相关。未来研究应探讨这种关系是否适用于非临终住院情况,以及其他环境中的姑息治疗是否会影响住院费用。