体育锻炼对老年男性血浆脂蛋白和载脂蛋白代谢的影响。

The effects of physical exercise on plasma lipoprotein and apolipoprotein metabolism in elderly men.

作者信息

Tamai T, Nakai T, Takai H, Fujiwara R, Miyabo S, Higuchi M, Kobayashi S

机构信息

Third Department of Internal Medicine, Fukui Medical School, Japan.

出版信息

J Gerontol. 1988 Jul;43(4):M75-9. doi: 10.1093/geronj/43.4.m75.

DOI:10.1093/geronj/43.4.m75

PMID:3385143

Abstract

The present study was undertaken to evaluate the effects of physical exercise on plasma lipoprotein and apolipoprotein metabolism in elderly men. We measured plasma concentrations of lipids, lipoproteins, and apolipoproteins (apo) in 12 elderly runners (OR), 12 elderly sedentary controls, 16 young runners (YR), and 15 young sedentary controls. Although there were no significant differences in plasma levels of cholesterol (Ch), triglyceride, and phospholipid between two old groups and between two young groups, OR and YR had decreased levels of VLDL-Ch (42% and 59% of respective control) and LDL-Ch (90%, 94%), and increased levels of HDL-Ch (133%, 112%), apo A-I (109%, 101%), and apo A-II (109%, 105%). These data indicate that physical exercise may have favorable effects on plasma concentrations of lipoproteins and apolipoproteins in OR as well as in YR, and affect HDL-lipids, HDL-proteins, and ratio of HDL-proteins/HDL-lipids.

摘要

本研究旨在评估体育锻炼对老年男性血浆脂蛋白和载脂蛋白代谢的影响。我们测量了12名老年跑步者（OR）、12名老年久坐对照者、16名年轻跑步者（YR）和15名年轻久坐对照者的血浆脂质、脂蛋白和载脂蛋白（apo）浓度。尽管两个老年组之间以及两个年轻组之间的血浆胆固醇（Ch）、甘油三酯和磷脂水平没有显著差异，但OR组和YR组的极低密度脂蛋白胆固醇（VLDL-Ch）水平降低（分别为各自对照组的42%和59%），低密度脂蛋白胆固醇（LDL-Ch）水平降低（90%，94%），高密度脂蛋白胆固醇（HDL-Ch）、载脂蛋白A-I（109%，101%）和载脂蛋白A-II（109%，105%）水平升高。这些数据表明，体育锻炼可能对OR组和YR组的血浆脂蛋白和载脂蛋白浓度产生有益影响，并影响高密度脂蛋白脂质、高密度脂蛋白蛋白质以及高密度脂蛋白蛋白质/高密度脂蛋白脂质的比例。