Kalra Aradhana, Kumar Prem, Parwan Deepika
Department of Reproductive Medicine, Milann Fertility, Delhi, India -
Department of General Surgery, Sarvodaya Hospital, Faridabad, India.
Minerva Obstet Gynecol. 2021 Apr;73(2):268-271. doi: 10.23736/S2724-606X.21.04772-9.
Myomectomy scar pregnancy is a rare intramural pregnancy in which gestational sac is implanted in the myometrium, in the previous myomectomy scar separate from endometrial cavity and fallopian tubes. Heterotopic pregnancy is presence of simultaneous gestation at two or more implantation sites. Our patient presented at 7 weeks, in-vitro fertilization (IVF) conception with previous four IVF failures and myomectomy 3 months prior. Transvaginal sonography revealed twin live pregnancies, one intrauterine and another in the posterior wall of the uterus distinctly separate from the endometrial cavity. Laparoscopy revealed a ruptured intramural pregnancy, another unruptured tubal pregnancy which was initially missed by USG. After laparoscopic management, intrauterine pregnancy continued resulting in live birth at 35 weeks. This case adds to the literature and highlights the importance of early diagnosis and timely intervention of a rare form of an ectopic gestation. This is the only reported case in literature with a heterotopic gestation and a coexistent myomectomy scar pregnancy and the only one resulting in successful live birth after laparoscopic management of a ruptured myomectomy scar pregnancy in a heterotopic gestation. Early diagnosis is important for salvaging the intrauterine gestation and one should actively look for them at viability scan especially in assisted reproductive technology (ART) conception and scarred uterus.
子宫肌瘤剔除术后瘢痕妊娠是一种罕见的肌壁间妊娠,妊娠囊着床于子宫肌层内,位于既往子宫肌瘤剔除术后瘢痕处,与子宫内膜腔及输卵管分离。异位妊娠是指在两个或更多着床部位同时发生妊娠。我们的患者孕7周就诊,通过体外受精(IVF)受孕,既往有4次IVF失败史,3个月前接受过子宫肌瘤剔除术。经阴道超声检查发现双胎存活妊娠,一个位于宫内,另一个位于子宫后壁,与子宫内膜腔明显分离。腹腔镜检查发现一个肌壁间妊娠破裂,另一个未破裂的输卵管妊娠最初超声检查未发现。经腹腔镜处理后,宫内妊娠继续,孕35周时顺产。该病例丰富了文献资料,突出了对这种罕见异位妊娠形式进行早期诊断和及时干预的重要性。这是文献中唯一报道的一例同时合并异位妊娠和子宫肌瘤剔除术后瘢痕妊娠的病例,也是唯一一例在腹腔镜处理异位妊娠中破裂的子宫肌瘤剔除术后瘢痕妊娠后成功顺产的病例。早期诊断对于挽救宫内妊娠很重要,在可行扫描时应积极寻找此类情况,尤其是在辅助生殖技术(ART)受孕和子宫有瘢痕的情况下。