Department of Surgery, St George Hospital, Gray St, Sydney, NSW, 2217, Australia.
School of Medicine, Western Sydney University, Sydney, NSW, 2751, Australia.
Obes Surg. 2021 Jul;31(7):2906-2912. doi: 10.1007/s11695-021-05335-8. Epub 2021 Apr 14.
There is a complex association between obesity, hiatal hernia (HH), and reflux. There is a deficiency of literature on the accuracy of preoperative high-resolution manometry (HRM) in detecting HH before both primary and revision bariatric surgery.
A retrospective analysis of a prospective database of all HRM performed before bariatric surgery from 2014 to 2019. An electronic medical records review was conducted. Sensitivity, specificity, and global diagnostic test accuracy were calculated.
Sixty-seven patients with HRM (mean age of 44.0 ± 11.3 years, body mass index 40.8 ± 6.9 kg/m) were eligible. Intraoperative diagnosis of HH was made in 37 patients (55.2% prevalence). The HRM sensitivity was 48.7% (95% confidence interval (CI) 31.9-65.6%), specificity 90.0% (95% CI 73.5-97.9%), and accuracy was 67.2% (95% CI 54.6-78.2%). Comparing primary (28) and revision (39) surgery, the sensitivity (37.5% vs 57.1%), specificity (75.0% vs 100%), and diagnostic accuracy (54.3% vs 76.3%) were comparable, with overlapping 95% CI. Endoscopy performed in 30 patients had a sensitivity of 25.5% (95% CI 6.8-49.9%), specificity of 100% (95% CI 75.3-100%), and accuracy of 57.8% (95% CI 38.5-75.5%) and was comparable to HRM.
High-resolution manometry for the detection of HH before bariatric surgery has a high specificity and maintains a high accuracy in both primary and revision bariatric surgery.
肥胖、食管裂孔疝(HH)和反流之间存在复杂的关联。在初次和再次减重手术之前,术前高分辨率测压(HRM)检测 HH 的准确性方面文献不足。
对 2014 年至 2019 年所有接受减重手术前进行的 HRM 的前瞻性数据库进行回顾性分析。进行电子病历回顾。计算了敏感性、特异性和总体诊断测试准确性。
67 名接受 HRM 的患者(平均年龄 44.0 ± 11.3 岁,体重指数 40.8 ± 6.9 kg/m)符合条件。37 名患者(55.2%的患病率)术中诊断为 HH。HRM 的敏感性为 48.7%(95%置信区间[CI] 31.9-65.6%),特异性为 90.0%(95%CI 73.5-97.9%),准确性为 67.2%(95%CI 54.6-78.2%)。比较初次(28 例)和再次(39 例)手术,敏感性(37.5% vs 57.1%)、特异性(75.0% vs 100%)和诊断准确性(54.3% vs 76.3%)相当,95%CI 重叠。在 30 名患者中进行的内镜检查的敏感性为 25.5%(95%CI 6.8-49.9%),特异性为 100%(95%CI 75.3-100%),准确性为 57.8%(95%CI 38.5-75.5%),与 HRM 相当。
在减重手术前检测 HH 的高分辨率测压具有很高的特异性,并在初次和再次减重手术中保持很高的准确性。