D'Elia Lorenzo, Barreca Antonella, Ferraresi Martina, Marciello Antonio, Rizzuto Antonietta, Sandri Luisa, Perosa Paolo Maurizio
SS Nefrologia e dialisi, Ospedale "E. Agnelli" di Pinerolo, ASLTO3, Torino, Italia.
Anatomia Patologica, AOU città della salute e della Scienza, Torino, Italia.
G Ital Nefrol. 2021 Apr 14;38(2):2021-vol2.
Multiple myeloma represents one of the main universal oncological diseases. Due to its clinical characteristics, it is often diagnosed only too late, when it has already determined systemic effects; this results in greater therapeutic difficulty and worse prognostic results. Through the clinical case discussed in this article, we want to focus on the often aspecific manifestations of this pathology and on the need for a correct clinical and diagnostic framework. The main renal manifestations secondary to the deposition of immunoglobulins in both the glomerular and tubular areas will also be examined.
多发性骨髓瘤是主要的全身性肿瘤疾病之一。由于其临床特征，该病往往确诊过晚，此时已经出现全身影响；这导致治疗难度加大，预后结果更差。通过本文所讨论的临床病例，我们希望关注这种病症常见的非特异性表现以及建立正确临床和诊断框架的必要性。我们还将研究免疫球蛋白在肾小球和肾小管区域沉积继发的主要肾脏表现。
