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医护人员配备的救护车与创伤性低血压患者在长时间院前停留后院内死亡率增加:一项全国性研究。

Physician-staffed ambulance and increased in-hospital mortality of hypotensive trauma patients following prolonged prehospital stay: A nationwide study.

机构信息

From the Department of Emergency and Critical Care Medicine (R.Y., J.Y., Y.N., J.S.), Keio University School of Medicine, Tokyo; and Department of Emergency Medicine (M.S.), Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.

出版信息

J Trauma Acute Care Surg. 2021 Aug 1;91(2):336-343. doi: 10.1097/TA.0000000000003239.

Abstract

BACKGROUND

The benefits of physician-staffed emergency medical services (EMS) for trauma patients remain unclear because of the conflicting results on survival. Some studies suggested potential delays in definitive hemostasis due to prolonged prehospital stay when physicians are dispatched to the scene. We examined hypotensive trauma patients who were transported by ambulance, with the hypothesis that physician-staffed ambulances would be associated with increased in-hospital mortality, compared with EMS personnel-staffed ambulances.

METHODS

A retrospective cohort study that included hypotensive trauma patients (systolic blood pressure ≤ 90 mm Hg at the scene) transported by ambulance was conducted using the Japan Trauma Data Bank (2004-2019). Physician-staffed ambulances are capable of resuscitative procedures, such as thoracotomy and surgical airway management, while EMS personnel-staffed ambulances could only provide advanced life support. In-hospital mortality and prehospital time until the hospital arrival were compared between patients who were classified based on the type of ambulance. Inverse probability weighting was conducted to adjust baseline characteristics including age, sex, comorbidities, mechanism of injury, vital signs at the scene, injury severity, and ambulance dispatch time.

RESULTS

Among 14,652 patients eligible for the study, 738 were transported by a physician-staffed ambulance. In-hospital mortality was higher in the physician-staffed ambulance than in the EMS personnel-staffed ambulance (201/699 [28.8%] vs. 2287/13,090 [17.5%]; odds ratio, 1.90 [1.61-2.26]; adjusted odds ratio, 1.22 [1.14-1.30]; p < 0.01), and the physician-staffed ambulance showed longer prehospital time (50 [36-66] vs. 37 [29-48] min, difference = 12 [11-12] min, p < 0.01). Such potential harm of the physician-staffed ambulance was only observed among patients who arrived at the hospital with persistent hypotension (systolic blood pressure < 90 mm Hg on hospital arrival) in subgroup analyses.

CONCLUSION

Physician-staffed ambulances were associated with prolonged prehospital stay and increased in-hospital mortality among hypotensive trauma patients compared with EMS personnel-staffed ambulance.

LEVEL OF EVIDENCE

Therapeutic, level IV.

摘要

背景

由于生存结果存在冲突,因此医师配备的紧急医疗服务(EMS)对创伤患者的益处仍不清楚。一些研究表明,由于当派遣医生到现场时,院前停留时间延长,可能会延迟确定性止血。我们检查了由救护车转运的低血压创伤患者,假设与 EMS 人员配备的救护车相比,医师配备的救护车会导致住院死亡率增加。

方法

使用日本创伤数据库(2004-2019 年)进行了一项回顾性队列研究,该研究包括由救护车转运的低血压创伤患者(现场收缩压≤90mmHg)。医师配备的救护车能够进行复苏程序,例如开胸术和手术气道管理,而 EMS 人员配备的救护车只能提供高级生命支持。根据救护车的类型对患者进行分类,并比较了住院死亡率和从医院到达前的院前时间。使用逆概率加权法调整了包括年龄、性别、合并症、损伤机制、现场生命体征、损伤严重程度和救护车派遣时间在内的基线特征。

结果

在符合研究条件的 14652 名患者中,有 738 名由医师配备的救护车转运。在医师配备的救护车中,住院死亡率高于 EMS 人员配备的救护车(201/699[28.8%]比 2287/13090[17.5%];比值比,1.90[1.61-2.26];调整后的比值比,1.22[1.14-1.30];p<0.01),并且医师配备的救护车的院前时间更长(50[36-66]比 37[29-48]min,差值=12[11-12]min,p<0.01)。在亚组分析中,只有在到达医院时持续低血压(到达医院时收缩压<90mmHg)的患者中观察到医师配备的救护车的这种潜在危害。

结论

与 EMS 人员配备的救护车相比,医师配备的救护车与低血压创伤患者的院前停留时间延长和住院死亡率增加有关。

证据水平

治疗性,IV 级。

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