Epidemiol Mikrobiol Imunol. 2021 Spring;70(1):62-67.
Reports of SARS-CoV-2 reinfections are on the rise. This study focused on reinfections in patients with confirmed COVID-19 in the Czech Republic. Between 1 March 2020 and 9 November 2020, 362 084 cases with the onset of symptoms before 31 October 2020 were reported. Overall, 28 cases of symptomatic SARS-CoV-2 reinfections were identified, 11 in males and 17 in females, age range 25-80 years, median age 46 years. The interval between the first and second episodes of the disease ranged from 101 to 231 days, and the median interval was 201.5 days. During both symptomatic episodes, all patients have been tested by RT-PCR. Altogether 26 patients (92.9%) have been tested negative after recovery from the first episode of COVID-19. Symptomatic reinfections occurred in nearly 0.2% of all patients at risk. Most patients with reinfection had mild symptoms in both episodes, and only three episodes were moderate to severe. Thus, reinfections may have been underdiagnosed. In summary, COVID-19 reinfections are possible and not exceptional.
SARS-CoV-2 再感染的报告正在增加。本研究关注的是捷克共和国确诊 COVID-19 患者的再感染情况。2020 年 3 月 1 日至 2020 年 11 月 9 日，报告了 362084 例发病前至 2020 年 10 月 31 日的病例。总体而言，确定了 28 例有症状的 SARS-CoV-2 再感染病例，男性 11 例，女性 17 例，年龄 25-80 岁，中位年龄 46 岁。两次疾病发作之间的间隔为 101-231 天，中位数间隔为 201.5 天。两次有症状的发作期间，所有患者均通过 RT-PCR 进行了检测。在首次感染 COVID-19 康复后，26 名患者（92.9%）的检测结果均为阴性。所有有风险的患者中，有近 0.2%的患者发生了症状性再感染。大多数再感染患者在两次发作中都有轻度症状，仅有三例为中度至重度。因此，再感染可能被漏诊了。总的来说，COVID-19 的再感染是可能的，而且并不罕见。
