Zhao Wenpeng, Hou Xiaopu, Li Honglu, Guo Jiang, Cai Liang, Duan Youjia, Du Hongliu, Shao Xihong, Diao Zhenying, Li Changqing
Department of Oncology Interventional Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
J Int Med Res. 2021 Apr;49(4):3000605211007722. doi: 10.1177/03000605211007722.
To summarize and analyze the imaging features and outcomes of patients with ruptured hepatocellular carcinoma (HCC) following transcatheter arterial chemoembolization (TACE).
We investigated all consecutive patients with HCC who received standardized TACE based on our hospital database. Ruptured HCCs were divided into three types according to their relationship with the liver capsule, determined by computed tomography or magnetic resonance imaging scans: Type I, portion of tumor cambered outwards ≤30%; Type II, portion of tumor cambered outwards >30% and <50%; and Type III, portion of tumor cambered outwards ≥50%.
There were 54, 40, and 26 patients with Type I, II, and III HCCs, respectively. Among these, eight patients developed ruptured tumors within 2 weeks after TACE, including one, two, and five patients with type I, II, and III ruptured HCCs, respectively. Patients with type III HCCs had a shorter median survival time than patients with type I-II HCCs.
Patients with type III HCCs might have a higher re-rupture rate and benefit less from emergency arterial embolization procedures than patients with type I-II HCCs.
总结并分析经动脉化疗栓塞术（TACE）后肝细胞癌（HCC）破裂患者的影像学特征及预后。
基于我院数据库，我们调查了所有接受标准化TACE治疗的连续性HCC患者。根据计算机断层扫描或磁共振成像扫描结果，将破裂的HCC根据其与肝包膜的关系分为三种类型：I型，肿瘤向外弯曲部分≤30%；II型，肿瘤向外弯曲部分>30%且<50%；III型，肿瘤向外弯曲部分≥50%。
分别有54例、40例和26例I型、II型和III型HCC患者。其中，8例患者在TACE后2周内发生肿瘤破裂，分别有1例、2例和5例I型、II型和III型破裂HCC患者。III型HCC患者的中位生存时间短于I-II型HCC患者。
与I-II型HCC患者相比，III型HCC患者可能具有更高的再破裂率，且从急诊动脉栓塞手术中获益较少。
