Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom
mSphere. 2021 Apr 14;6(2):e00210-21. doi: 10.1128/mSphere.00210-21.
Clare Harding works on the metal biology of the parasite In this mSphere of Influence article, she reflects on how two papers from the laboratory of Maria Mota, "Host-mediated regulation of superinfection in malaria" by Portugal et al. (S. Portugal, C. Carret, M. Recker, A. E. Armitage, et al., Nat Med 17:732-737, 2011, https://doi.org/10.1038/nm.2368) and "Nutrient sensing modulates malaria parasite virulence" by Mancio-Silva et al. (L. Mancio-Silva, K. Slavic, M. T. Grilo Ruivo, A. R. Grosso, et al., Nature 547:213-216, 2017, https://doi.org/10.1038/nature23009), made an impact on her understanding of host-pathogen interactions by examining the complex interplay between parasites and their hosts' nutritional status.
克莱尔·哈丁研究寄生虫的金属生物学。在这篇《mSphere 影响力》文章中，她回顾了玛丽亚·莫塔实验室的两篇论文，葡萄牙等人的“疟疾中超感染的宿主介导调控”（S. Portugal, C. Carret, M. Recker, A. E. Armitage, 等人，Nat Med 17:732-737, 2011, https://doi.org/10.1038/nm.2368）和曼西奥-席尔瓦等人的“营养感应调节疟原虫毒力”（L. Mancio-Silva, K. Slavic, M. T. Grilo Ruivo, A. R. Grosso, 等人，Nature 547:213-216, 2017, https://doi.org/10.1038/nature23009）如何通过研究寄生虫与其宿主营养状况之间的复杂相互作用，对她理解宿主-病原体相互作用产生了影响。
