Xue Ling-Wei, Han Yong-Jun, Luo Xiao-Qiang
Acta Chim Slov. 2019 Sep;66(3):622-628.
A pair of oxidovanadium(V) complexes, [VOLL1] (1) and [VOLL2] (2), where L is the dianionic form of the hydrazone ligand N'-(5-chloro-2-hydroxybenzylidene)pivalohydrazide (H2L), L1 and L2 are the deprotonated forms of 3-hydroxy-2-methyl-4H-pyran-4-one (HL1; maltol) and 2-ethyl-3-hydroxy-4H-pyran-4-one (HL2; ethyl maltol), respectively, have been prepared and characterized by elemental analyses, IR and UV-Vis spectroscopy, and single-crystal X-ray crystallographic determination. The V atoms in the complexes are in octahedral coordination, with the hydrazone ligand coordinated to the V atoms through the phenolate O, imino N and enolate O atoms, and with the pyrone ligands coordinated to the V atoms through two O atoms. The effect of the compounds on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was studied.
合成了一对氧化钒（V）配合物，即[VOLL1]（1）和[VOLL2]（2），其中L是腙配体N'-(5-氯-2-羟基亚苄基)新戊酰肼（H2L）的二价阴离子形式，L1和L2分别是3-羟基-2-甲基-4H-吡喃-4-酮（HL1；麦芽酚）和2-乙基-3-羟基-4H-吡喃-4-酮（HL2；乙基麦芽酚）的去质子化形式。通过元素分析、红外光谱和紫外可见光谱以及单晶X射线晶体学测定对其进行了表征。配合物中的钒原子呈八面体配位，腙配体通过酚盐O、亚氨基N和烯醇盐O原子与钒原子配位，吡喃酮配体通过两个O原子与钒原子配位。研究了这些化合物对金黄色葡萄球菌、大肠杆菌和白色念珠菌的抗菌活性。
