Suppr超能文献

无听力不对称的前庭神经鞘瘤患者的病例系列。

Case series of vestibular schwannoma patients with no asymmetry in hearing.

机构信息

West Virginia University, Department of Otolaryngology, Morgantown, WV 26505, United States of America.

West Virginia University, School of Medicine, Morgantown, WV 26505, United States of America.

出版信息

Am J Otolaryngol. 2021 Sep-Oct;42(5):103034. doi: 10.1016/j.amjoto.2021.103034. Epub 2021 Apr 7.

Abstract

OBJECTIVE

(1) Describe the presenting symptoms and tumor characteristics of patients who are diagnosed with a vestibular schwannoma (VS) with normal hearing or symmetric hearing loss, and (2) report the prospective growth and treatment of each tumor.

METHODS

This is a retrospective cohort study of acoustic neuroma patients who were found to have a VS and normal or symmetric hearing loss at a single tertiary care academic center from 1999 to 2012. Medical records were reviewed collecting the following information: patient demographics, symptoms, MRI characteristics, and treatment modality.

RESULTS

15/195 (7.7%) patients met criteria for the study. Dizziness was the most common presenting symptom occurring in 9 subjects (60%), followed by headache in 6 (40%), vision changes in 5 (33%), tinnitus in 5 (33%), and unilateral hearing loss in 1 (7%). The average tumor size was 1.07 cm (range 0.3-2.2 cm). Eight (53%) patients presented with intracanalicular tumors. Growth was observed in 6 subjects (40%) with average growth rate in those who exhibited mean growth of 1.8 mm per year. Treatment consisted of surgical removal in 4 cases (27%), gamma knife therapy in 1 (7%), and observation or loss to follow-up in 10 (66%).

CONCLUSIONS

The incidence of VS with normal hearing was 7.7% Patients with VSs who do not exhibit unilateral hearing loss present most commonly with dizziness. Most of our patients had small, intracanalicular tumors with the largest tumor measuring 2.2 cm in greatest dimension. Of those who were managed conservatively with repeat imaging and observation, most showed tumor growth.

摘要

目的

(1) 描述诊断为具有正常听力或对称听力损失的前庭神经鞘瘤(VS)患者的症状和肿瘤特征,以及 (2) 报告每个肿瘤的预期生长和治疗情况。

方法

这是一项回顾性队列研究,研究对象为 1999 年至 2012 年期间在一家三级学术医疗中心发现具有 VS 和正常或对称听力损失的听神经瘤患者。回顾病历,收集以下信息:患者人口统计学、症状、MRI 特征和治疗方式。

结果

15/195(7.7%)例患者符合研究标准。头晕是最常见的症状,有 9 例(60%)患者出现头晕,其次是头痛 6 例(40%)、视力改变 5 例(33%)、耳鸣 5 例(33%)和单侧听力损失 1 例(7%)。肿瘤平均大小为 1.07cm(范围 0.3-2.2cm)。8 例(53%)患者表现为管内肿瘤。有 6 例(40%)患者观察到肿瘤生长,其中表现出平均生长速度的患者平均每年生长 1.8mm。治疗包括手术切除 4 例(27%)、伽玛刀治疗 1 例(7%)和观察或失访 10 例(66%)。

结论

具有正常听力的 VS 发生率为 7.7%。未出现单侧听力损失的 VS 患者最常见的症状是头晕。我们的大多数患者都有小的、管内肿瘤,最大的肿瘤直径为 2.2cm。在接受重复影像学检查和观察的保守治疗的患者中,大多数患者的肿瘤生长。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验