Burger J, Gochfeld M
Rutgers University, Piscataway, New Jersey 08855.
J Toxicol Environ Health. 1988;24(2):173-82. doi: 10.1080/15287398809531151.
Exposure to lead early in life is known to affect behavioral development. Young common terns (Sterna hirundo) were injected with lead nitrate solution (0.2-1.2 mg/g) or sterile saline to examine the dose-response curve for behavioral effects. Exposed chicks received a dose of lead on d 3 or on d 3 and 7. Behavioral tests 2 d after each injection included visual cliff performance, locomotion, and righting response. Survival depended not only on dose but also on whether chicks received one or two injections. Despite the narrow range of doses, behavioral differences were noted for all measures as a function of dose. The initial lead dose affected behavior more than the second dose, despite the fact that birds receiving a divided dose were more likely to die.
已知生命早期接触铅会影响行为发育。给幼年普通燕鸥（Sterna hirundo）注射硝酸铅溶液（0.2 - 1.2毫克/克）或无菌生理盐水，以研究行为效应的剂量反应曲线。暴露组雏鸟在第3天或第3天和第7天接受铅剂量。每次注射后2天进行行为测试，包括视觉悬崖表现、运动能力和翻正反应。存活率不仅取决于剂量，还取决于雏鸟接受一次还是两次注射。尽管剂量范围狭窄，但所有测量指标的行为差异都与剂量有关。初始铅剂量对行为的影响大于第二次剂量，尽管接受分次剂量的鸟类更有可能死亡。
