Torre-Castro Juan, Moya-Martínez Cristina, Sangüeza Omar, Requena Luis
Department of Dermatology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain; and.
Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC.
Am J Dermatopathol. 2021 Nov 1;43(11):835-837. doi: 10.1097/DAD.0000000000001940.
Microcystic adnexal carcinoma (MAC) is a low-grade malignant neoplasm of slow growth and low metastatic potential, but locally aggressive. Architecturally, MAC is usually a poorly circumscribed neoplasm that tends to extend deeply into the dermis and subcutaneous tissue. We present here a lesion in which the histopathologic study showed a well-demarcated nodular lesion involving the mid dermis and composed of small cystic keratinous structures, solid aggregates of pale squamous cells without cytologic atypia and ductal structures. Although these neoplastic components resembled those of MAC, the sharp delimitation of the lesion as well as the absence of deep extension and perineural involvement supported the benign nature of this lesion. We have named this neoplasm microcystic adnexal adenoma, as the benign counterpart of MAC.
微囊性附属器癌（MAC）是一种生长缓慢、转移潜能低的低级别恶性肿瘤，但具有局部侵袭性。从结构上看，MAC通常是边界不清的肿瘤，倾向于深入真皮和皮下组织。我们在此呈现一个病变，其组织病理学研究显示为一个界限清楚的结节性病变，累及真皮中部，由小的囊性角质结构、无细胞学异型性的淡染鳞状细胞实性团块以及导管结构组成。尽管这些肿瘤成分与MAC相似，但病变的清晰界限以及无深部浸润和神经周围侵犯支持了该病变的良性性质。我们将这种肿瘤命名为微囊性附属器腺瘤，作为MAC的良性对应物。
