Masaki N, Ikeda H, Hayabuchi N, Niibe H, Kaneta H, Morita K, Horiuchi J, Watanabe S
Dept. of Radiology, Osaka Univ.
Gan No Rinsho. 1988 Apr;34(5):581-8.
A retrospective analysis of 1514 patients with non-Hodgkin's lymphoma treated between 1972 and 1985 was performed. Of these cases, 114 with histology of low-grade malignancy and 750 with intermediate malignancy were localized in the head and neck. All patients received definitive course of radiation therapy, including 390 cases with adjuvant chemotherapy. For cases with low-grade malignancy, all cases were locally controlled and five-year relapse free survival rates were 85% in stage I, and 75% in stage II. For cases with intermediate malignancy, local control rates were 97% in stage I, and 87% in stage II. Five-year survival rates were 67% in stage I and 50% in stage II. There were no benefit on survival rates from adjuvant use of chemotherapy with radiation therapy as compared to radiation therapy alone.
对1972年至1985年间接受治疗的1514例非霍奇金淋巴瘤患者进行了回顾性分析。在这些病例中,114例组织学为低度恶性,750例为中度恶性,病变局限于头颈部。所有患者均接受了根治性放射治疗,其中390例接受了辅助化疗。对于低度恶性病例,所有病例均实现局部控制,I期五年无复发生存率为85%,II期为75%。对于中度恶性病例,I期局部控制率为97%,II期为87%。I期五年生存率为67%,II期为50%。与单纯放射治疗相比,辅助化疗联合放射治疗对生存率没有益处。