Horiuchi J, Shibya H, Matsumoto S, Kamiyama R
Dept. of Radiology, Tokyo Med. & Dent. Univ.
Gan No Rinsho. 1988 Apr;34(5):619-30.
An analysis was made on localized extranodal non-Hodgkin's lymphoma in the maxillo-facial region treated with radiation. Histopathological evaluation was reviewed by Rappaport classification and Working Formulation (WF). High grade histology of WF was rather frequent (32%) compared to Waldeyer's (NHL) (7%). Prognosis of the disease was highly influenced by histopathologic grade in WF; five-year survival rate was 100% with low grade, 65.6% with intermediate grade and 33.3% with high grade. Marginal relapse was rare after radiation dose of 30-50 Gy, however, there was a high incidence of bone and/or soft tissue relapses. Bone marrow biopsy and bone scintigram were useful examinations in the staging procedure of extranodal NHL.