靶向阿尔茨海默病中的淀粉样蛋白。
TAM-ping down amyloid in Alzheimer's disease.
机构信息
Department of Neurology, Stanford University, Stanford, CA, USA.
Wu-Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
出版信息
Nat Immunol. 2021 May;22(5):543-544. doi: 10.1038/s41590-021-00918-0.
Abstract
The TAM receptor kinases Axl and Mer are critical for microglial recognition and clearance of accumulating amyloid in transgenic models of Alzheimer’s disease.
摘要
TAM 受体激酶 Axl 和 Mer 对于阿尔茨海默病转基因模型中小胶质细胞识别和清除积累的淀粉样蛋白至关重要。
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