Wang Mei-Fang, Lin Li, Li Lin-Feng
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Infect Drug Resist. 2021 Apr 9;14:1375-1379. doi: 10.2147/IDR.S302195. eCollection 2021.
Giant condyloma acuminatum (GCA), also called Buschke-Löwenstein tumor, presents as a verrucous infiltrating lesion and is caused by sexual transmission of human papilloma virus. The optimal treatment is controversial and there are no standard guidelines because of its rarity and frequent recurrence. It has a relatively high local recurrence rate.
We here report eight patients (six men and two women) with GCA whose lesions were successfully treated topically with traditional Chinese medicine (TCM) preparations, paiteling.
We administered topical TCM preparations to eight patients diagnosed with GCA who had refused surgery. The treatment process included three stages, their durations depending on the speed of resolution of the lesions and the results of visual inspection with acetic acid.
No significant complications occurred in any patient. The functional and esthetic outcomes were satisfactory. No recurrences were detected during follow-up.
Topical treatment with TCM preparations may be a good alternative to surgery or other traditional methods for the treatment of GCA. This treatment has the advantages of being non-invasive, painless, and having a low risk of recurrence, and may be a useful adjunct to mainstream medical treatments.
巨大尖锐湿疣（GCA），也称为Buschke-Löwenstein肿瘤，表现为疣状浸润性病变，由人乳头瘤病毒性传播引起。由于其罕见性和频繁复发，最佳治疗方法存在争议且没有标准指南。其局部复发率相对较高。
我们在此报告8例巨大尖锐湿疣患者（6例男性和2例女性），其病变通过中药制剂派特灵成功进行了局部治疗。
我们对8例诊断为巨大尖锐湿疣且拒绝手术的患者给予局部中药制剂治疗。治疗过程包括三个阶段，其持续时间取决于病变消退速度和醋酸目视检查结果。
所有患者均未发生明显并发症。功能和美学效果令人满意。随访期间未发现复发。
中药制剂局部治疗可能是巨大尖锐湿疣手术或其他传统治疗方法的良好替代方案。该治疗具有无创、无痛、复发风险低的优点，可能是主流医学治疗的有用辅助手段。
