De Schrijver S, Theate I, Vanhooteghem O
Dermatology Department, CHU UCL Namur, Site Sainte Elisabeth, Place Louise Godin 15, 5000 Namur, Belgium.
Institute of Pathology and Genetics (IPG), Avenue George-Lemaître 25, 6041 Gosselies, Belgium.
Case Rep Dermatol Med. 2021 Mar 22;2021:6672528. doi: 10.1155/2021/6672528. eCollection 2021.
Halo nevi are often considered benign, and the possibility of malignancy is not always clear to practitioners. We present two case reports suggesting that a halo nevus appearance can be seen in melanoma, even in young adults. A literature search for halo nevi revealing melanoma shows that this is a very rare condition. . This report of two young patients indicates the importance of obtaining a detailed history to detect warning signs such as itching, pain, spontaneous bleeding, and previous alterations according to the patient, including a previously totally black colour in an already fully regressed melanoma.
The risk of a halo nevus being malignant is higher if there is only one unique halo nevus and no personal or familial history of vitiligo. We postulate that a regressing atypical nevus or a regressing melanoma may be induced by an immunologic reaction as halo nevus type of clinical picture.
晕痣通常被认为是良性的,从业者对其恶变的可能性并不总是很清楚。我们报告两例病例,提示即使在年轻人中,黑色素瘤也可表现为晕痣外观。检索显示晕痣合并黑色素瘤的文献发现,这是一种非常罕见的情况。 这份关于两名年轻患者的报告表明,详细询问病史以发现诸如瘙痒、疼痛、自发出血等警示信号以及患者之前所述的变化(包括已完全消退的黑色素瘤曾完全呈黑色)的重要性。
如果只有一个孤立的晕痣且无白癜风个人史或家族史,则晕痣恶变的风险较高。我们推测,免疫反应可能会诱发正在消退的非典型痣或正在消退的黑色素瘤呈现晕痣型临床表现。