Kim Min-Ju, Kim Jung-In, Ryu Chung-Ho, Kang Min-Jung
Bio-Food Research Center, Hurom Co., Ltd., Gyeongnam 50969, Korea.
Institute of Digital Anti-Aging Healthcare, Inje University, Gyeongnam 50834, Korea.
Prev Nutr Food Sci. 2021 Mar 31;26(1):12-20. doi: 10.3746/pnf.2021.26.1.12.
This study investigated the effects of fermented beverage, kale/apple juice containing 5% vinegar in subjects with metabolic syndrome. Subjects were randomly assigned to receive 250 mL fermented beverage or water containing fructose, glucose, and sucrose twice daily for 10 weeks. Consumption of the fermented beverage significantly decreased plasma triglyceride, thiobarbituric acid reactive substances (TBARS), tumor necrosis factor (TNF)-α, and high sensitivity C-reactive protein (hs-CRP) levels compared to baseline values (<0.05). Furthermore, consumption of the fermented beverage significantly decreased homeostasis model assessment for insulin resistance (HOMA-IR) values and atherogenic indexes compared with baseline values (<0.05). In the control group, plasma triglyceride, TBARS, TNF-α, and hs-CRP levels, atherogenic indexes, and HOMA-IR values did not significantly differ pre-and post-treatment. The fermented beverage inhibited the activities of α-glucosidase and pancreatic lipase , therefore could be helpful in alleviating metabolic syndrome in subjects with metabolic syndrome.
本研究调查了含5%醋的发酵饮料、羽衣甘蓝/苹果汁对代谢综合征患者的影响。受试者被随机分为两组,每天两次分别饮用250毫升发酵饮料或含有果糖、葡萄糖和蔗糖的水,持续10周。与基线值相比,饮用发酵饮料显著降低了血浆甘油三酯、硫代巴比妥酸反应性物质(TBARS)、肿瘤坏死因子(TNF)-α和高敏C反应蛋白(hs-CRP)水平(<0.05)。此外,与基线值相比,饮用发酵饮料显著降低了胰岛素抵抗稳态模型评估(HOMA-IR)值和动脉粥样硬化指数(<0.05)。在对照组中,治疗前后血浆甘油三酯、TBARS、TNF-α和hs-CRP水平、动脉粥样硬化指数和HOMA-IR值无显著差异。发酵饮料抑制了α-葡萄糖苷酶和胰脂肪酶的活性,因此可能有助于缓解代谢综合征患者的代谢综合征。