Abbasian Maryam, Delvarianzadeh Mehri, Ebrahimi Hossein, Khosravi Farideh, Nourozi Pirasteh
School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran.
Diabetes Metab Syndr. 2018 Jul;12(4):497-500. doi: 10.1016/j.dsx.2018.03.015. Epub 2018 Mar 16.
This study aimed to investigate the relationship between the total antioxidant capacity (TAC) and Malondialdehyde (MDA) with number of metabolic syndrome (Mets) components on the personnel working in Shahroud University of Medical Sciences.
This cross-sectional study was conducted on 167 personnel aged 30-60 years old. ATP III criteria were used to diagnose patients with MetS. Oxidative stress indicators were measured. The data was analyzed via one-way ANOVA, and Pearson and Spearman correlation coefficients.
The result showed that TAC had a significant positive correlation with HDL and a significant negative correlation with abdominal obesity. In addition, there was a significant positive association between the level of MDA and age, BMI, abdominal obesity, diastolic blood pressure, triglycerides, and LDL; however, it had a negative significant correlation with HDL.
The measurement of TAC and MDA biomarkers can increase the early diagnosis of patients at risk of developing Mets.
本研究旨在调查沙赫鲁德医科大学工作人员的总抗氧化能力（TAC）和丙二醛（MDA）与代谢综合征（Mets）组分数量之间的关系。
本横断面研究对167名年龄在30至60岁之间的工作人员进行。采用ATP III标准诊断代谢综合征患者。测量氧化应激指标。数据通过单因素方差分析以及Pearson和Spearman相关系数进行分析。
结果显示，TAC与高密度脂蛋白（HDL）呈显著正相关，与腹型肥胖呈显著负相关。此外，MDA水平与年龄、体重指数（BMI）、腹型肥胖、舒张压、甘油三酯和低密度脂蛋白（LDL）之间存在显著正相关；然而，它与HDL呈显著负相关。
测量TAC和MDA生物标志物可提高对有发生Mets风险患者的早期诊断。
Zotero 插件