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具有抗成瘾潜力的植物。

Plants with Anti-Addictive Potential.

作者信息

Konrath Eduardo Luis, Arbo Marcelo Dutra, Arbo Bruno Dutra, Hort Mariana Appel, Elisabetsky Elaine, Leal Mirna Bainy

机构信息

Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.

Departamento de Farmacologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.

出版信息

Adv Exp Med Biol. 2021;1308:185-215. doi: 10.1007/978-3-030-64872-5_14.

Abstract

Drug addiction is prevalent among individuals of modern society, being a major cause of disability and premature loss of life. Although the drug addiction have profound social, economical and health impact in the world population, its management remains a challenge as available pharmacological treatments remains ineffective for most people. The limited efficacy and adverse effects have led to a search for alternative therapies to treat drug addiction. In this context, natural products are an important source for new chemical substances with a potential therapeutic applicability. Therefore, this chapter will present data obtained after an extensive literature search regarding the use of medicinal plants as a pharmacological alternative for drug addiction treatment.

摘要

药物成瘾在现代社会人群中普遍存在,是导致残疾和过早死亡的主要原因。尽管药物成瘾对全球人口有着深远的社会、经济和健康影响,但其治疗仍然是一项挑战,因为现有的药物治疗对大多数人来说效果不佳。疗效有限和副作用促使人们寻找治疗药物成瘾的替代疗法。在这种背景下,天然产物是具有潜在治疗适用性的新化学物质的重要来源。因此,本章将展示在广泛文献检索后获得的数据,内容涉及药用植物作为药物成瘾治疗的药理学替代方法的应用。

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