Department of Orthopaedics and Musculoskeletal Science, Division of Surgery and Interventional Science, University College London, London, United Kingdom.
Division of Medicine, Northwick Park Hospital, London, United Kingdom.
Pain. 2022 Feb 1;163(2):214-257. doi: 10.1097/j.pain.0000000000002302.
Our objective was to investigate the effectiveness of booster sessions after self-management interventions as a means of maintaining self-management behaviours in the treatment of chronic musculoskeletal pain. We searched MEDLINE, EMBASE, Science Citation Index, Cochrane Central Register of Controlled Trials, and PsychINFO. Two authors independently identified eligible trials and collected data. We calculated the odds ratio for the analyses of dichotomous data and standardised mean differences (SMDs) with 95% confidence interval (CI) for continuous variables. Our search identified 14 studies with a total of 1695 patients. All studies were at high risk of bias and provided very low quality evidence. For the primary outcomes, booster sessions had no evidence of an effect on improving patient-reported outcomes on physical function (SMD -0.13, 95% CI -0.32 to -0.06; P = 0.18), pain-related disability (SMD -0.16, 95% CI -0.36 to 0.03; P = 0.11), and pain self-efficacy (SMD 0.15, 95% CI -0.07 to 0.36; P = 0.18). For the secondary outcomes, booster sessions caused a significant reduction in patient-reported pain catastrophising (SMD -0.42, 95% CI -0.64 to -0.19; P = 0.0004) and no evidence of an effect on patient-reported pain intensity, depression, coping, or treatment adherence. There is currently little evidence that booster sessions are an effective way to prolong positive treatment effects or improve symptoms of long-term musculoskeletal conditions after self-management interventions. However, the studies were few with high heterogeneity, high risk of bias, and overall low quality of evidence. Our review argues against including booster sessions routinely to self-management interventions for the purpose of behaviour maintenance.
我们的目的是调查自我管理干预后的强化疗程作为维持慢性肌肉骨骼疼痛治疗中自我管理行为的一种手段的有效性。我们检索了 MEDLINE、EMBASE、科学引文索引、Cochrane 对照试验中心注册库和 PsychINFO。两位作者独立确定了合格的试验并收集了数据。我们计算了二分类数据的优势比和连续变量的标准化均数差(SMD)及其 95%置信区间(CI)。我们的搜索确定了 14 项研究,共有 1695 名患者。所有研究均存在高偏倚风险,且仅提供了极低质量的证据。对于主要结局,强化疗程对改善患者报告的物理功能结局(SMD -0.13,95%CI -0.32 至 -0.06;P = 0.18)、疼痛相关残疾(SMD -0.16,95%CI -0.36 至 0.03;P = 0.11)和疼痛自我效能(SMD 0.15,95%CI -0.07 至 0.36;P = 0.18)均无证据表明有效。对于次要结局,强化疗程可显著降低患者报告的疼痛灾难化(SMD -0.42,95%CI -0.64 至 -0.19;P = 0.0004),但对患者报告的疼痛强度、抑郁、应对或治疗依从性无影响。目前,几乎没有证据表明强化疗程是延长自我管理干预后积极治疗效果或改善长期肌肉骨骼疾病症状的有效方法。然而,这些研究数量较少,存在高度异质性、高偏倚风险和总体低质量证据。我们的综述反对将强化疗程常规纳入自我管理干预以维持行为。