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直肠脱垂手术后与直肠脱垂合并盆腔器官脱垂手术后的术后并发症和复发率。

Postoperative complications and recurrence rates after rectal prolapse surgery versus combined rectal prolapse and pelvic organ prolapse surgery.

机构信息

Women's Health Institute, Division of Urogynecology and Pelvic Floor Disorders, Cleveland Clinic Foundation, 9500 Euclid Avenue, Mailcode A81, Cleveland, OH, 44195, USA.

Department of Urology, Division of Female Urology, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

Int Urogynecol J. 2021 Sep;32(9):2401-2411. doi: 10.1007/s00192-021-04778-y. Epub 2021 Apr 17.

Abstract

INTRODUCTION AND HYPOTHESIS

Our primary objectives were to compare < 30-day postoperative complications and RP recurrence rates after RP-only surgery and combined surgery. Our secondary objectives were to determine preoperative predictors of < 30-day complications and RP recurrence.

METHODS

A prospective IRB-approved cohort study was performed at a single tertiary care center from 2017 to 2020. Female patients with symptomatic RP underwent either RP-only surgery or combined surgery based on the discretion of the colorectal and FPMRS surgeons. Primary outcome measures were < 30-day complications separated into Clavien-Dindo (CD) classes and rectal prolapse on physical examination.

RESULTS

Seventy women had RP-only surgery and 45 had combined surgery with a mean follow-up time of 208 days. Sixty-eight percent underwent abdominal RP repair, and 32% underwent perineal RP repair. Twenty percent had one or more complications, 14% in the RP-only group and 29% in the combined surgery group (p = 0.06). On multivariate analysis, combined surgery patients had a 30% increased risk of complications compared to RP-only surgery patients (RR = 1.3). Most of these complications were minor (14/17, 82.4%) and categorized as CD I or II, including urinary retention and UTI. Twelve percent of this cohort had RP recurrence, 11% in the RP-only group and 13% in the combined surgery group (p = 0.76). Preoperative risk factors for RP recurrence included a primary complaint of rectal bleeding (RR 5.5) and reporting stools consistent with Bristol Stool Scale of 1 (RR 2.1).

CONCLUSION

Patients undergoing combined RP + POP surgery had a higher risk of complications and equivalent RP recurrence rates compared to patients undergoing RP-only surgery.

摘要

引言和假设

我们的主要目标是比较单纯前列腺切除术(RP)和联合手术治疗后 30 天内的术后并发症和 RP 复发率。我们的次要目标是确定 30 天内并发症和 RP 复发的术前预测因素。

方法

在 2017 年至 2020 年期间,在一家单一的三级护理中心进行了一项前瞻性 IRB 批准的队列研究。根据结直肠和 FPMRS 外科医生的判断,有症状的 RP 女性患者接受 RP 或联合手术。主要观察指标是<30 天的并发症,分为 Clavien-Dindo(CD)分级和直肠脱垂的体格检查。

结果

70 名女性患者接受了单纯 RP 手术,45 名女性患者接受了联合手术,平均随访时间为 208 天。68%的患者接受了腹部 RP 修复,32%的患者接受了经会阴 RP 修复。20%的患者发生了一种或多种并发症,RP 组中为 14%,联合手术组中为 29%(p=0.06)。多变量分析显示,与单纯 RP 手术相比,联合手术组患者的并发症风险增加了 30%(RR=1.3)。这些并发症大多是轻微的(17 例中有 14 例,82.4%),属于 CD I 或 II 级,包括尿潴留和尿路感染。本队列中有 12%的患者发生 RP 复发,RP 组中为 11%,联合手术组中为 13%(p=0.76)。RP 复发的术前危险因素包括主要抱怨为直肠出血(RR 5.5)和报告粪便符合布里斯托粪便量表 1 级(RR 2.1)。

结论

与单纯 RP 手术相比,接受联合 RP+POP 手术的患者并发症风险更高,RP 复发率相当。

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