Trunin Yu Yu, Golanov A V, Konovalov A N, Pronin I N, Zagirov R I, Ryzhova M V, Kadyrov Sh U, Igoshina E N
Burdenko Neurosurgical Center, Moscow, Russia.
Zh Vopr Neirokhir Im N N Burdenko. 2021;85(2):34-46. doi: 10.17116/neiro20218502134.
Complex management of patients with intracranial pilocytic astrocytoma (PA) consists of surgical treatment, drug therapy (mainly in young children) and radiotherapy. For many years, radiotherapy (RT) has been a standard for residual tumors, recurrence or continued growth of PA. Currently, stereotactic radiosurgery and radiotherapy are preferred for PA, because these procedures are characterized by high conformity and selectivity, precise irradiation of tumor with minimal damage to surrounding intact tissues. Stereotaxic approach is very important since PAs are localized near functionally significant and radiosensitive brain structures in most cases. There is significant experience of single-center studies devoted to radiotherapy of patients with PA at the Department of Neuroradiosurgery of the Burdenko Neurosurgery Center. In this research, the authors analyzed the results of stereotactic irradiation of 430 patients with PA for the period from 2005 to 2018.
颅内毛细胞型星形细胞瘤（PA）患者的综合管理包括手术治疗、药物治疗（主要用于幼儿）和放射治疗。多年来，放射治疗（RT）一直是PA残留肿瘤、复发或持续生长的标准治疗方法。目前，立体定向放射外科和放射治疗是PA的首选治疗方法，因为这些治疗方法具有高适形性和选择性的特点，能够在对周围完整组织损伤最小的情况下精确照射肿瘤。立体定向方法非常重要，因为在大多数情况下，PA位于功能重要且对放射敏感的脑结构附近。布尔坚科神经外科中心神经放射外科部有关于PA患者放射治疗的单中心研究的丰富经验。在这项研究中，作者分析了2005年至2018年期间430例PA患者的立体定向照射结果。
