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[立体定向脑电图(SEEG):用于癫痫诊断和治疗的现代深部电极植入方法的简要历史回顾]

[Stereoelectroencephalography (seeg): a brief historical review of modern deep electrode implantation methods used for diagnosis and treatment of epilepsy].

作者信息

Khapov I V, Melikyan A G

机构信息

Burdenko Neurosurgical Center, Moscow, Russia.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2021;85(2):99-106. doi: 10.17116/neiro20218502199.

DOI:10.17116/neiro20218502199
PMID:33864674
Abstract

More than 30% of patients with symptomatic epilepsy are resistant to drug therapy and therefore surgical treatment is the method of choice for such patients. Search and localization of the epileptogenic zone and all parts of the neural networks involved in stereotypic seizures are the most important objectives of pre-surgical evaluation and the prerequisite for the successful surgery. In the last decade, stereotactic implantation of multiple intracerebral multi-contact electrodes (SEEG) has been increasingly used for this purpose. The article includes a brief history of SEEG and a description of the major techniques for stereotactic implantation of electrodes. Information on accuracy (errors and deviations from planned target) and on complications are summarized. The data on the clinical value of the method and how these data affected the results of subsequent treatment are highlighted. The method of thermocoagulation and its results are briefly considered.

摘要

超过30%的症状性癫痫患者对药物治疗耐药,因此手术治疗是这类患者的首选方法。寻找致痫区以及参与刻板性发作的神经网络的所有部分是术前评估的最重要目标,也是手术成功的前提条件。在过去十年中,立体定向植入多个脑内多触点电极(SEEG)越来越多地用于此目的。本文包括SEEG的简史以及电极立体定向植入的主要技术描述。总结了关于准确性(与计划靶点的误差和偏差)和并发症的信息。突出了该方法临床价值的数据以及这些数据如何影响后续治疗结果。简要考虑了热凝方法及其结果。

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