急性冠状动脉综合征中甲状腺激素改变的预后意义——系统评价。
Prognostic implications of thyroid hormone alterations in acute coronary syndrome-A systematic review.
机构信息
Academics & Research Department, Batra Heart Center, Batra Hospital and Medical Research Center, New Delhi, India; Labratory of Disease Dynamics and Molecular Epidemiology, Amity Institute of Public Health, Amity University Campus, Noida, Uttar Pradesh, India.
Academics & Research Department, Batra Heart Center, Batra Hospital and Medical Research Center, New Delhi, India.
出版信息
Indian Heart J. 2021 Mar-Apr;73(2):143-148. doi: 10.1016/j.ihj.2020.11.147. Epub 2020 Nov 23.
Abstract
There is considerable association of thyroid function and the cardiovascular system during various acute systemic illnesses. It is well established that the normal thyroid homeostasis is known to alter in disease states including the acute coronary syndromes (ACS). Abnormal thyroid hormonal status has been shown to be related to worse outcomes and prognosis. This review focuses on the relationship of alterations in thyroid function and its influence on the pathophysiological mechanisms and cardiovascular hemodynamics in ACS and based upon the literature, summarises all the existing evidence to this date on this subject. The data largely points out that low levels of triiodothyronine (T3) levels seen in ACS might be useful in prognosticating the outcomes of ACS.
摘要
在各种急性全身性疾病中，甲状腺功能与心血管系统有很大的关联。众所周知，正常的甲状腺内稳态在包括急性冠状动脉综合征（ACS）在内的疾病状态下会发生改变。已经证明，异常的甲状腺激素状态与更差的结局和预后有关。这篇综述重点关注甲状腺功能改变及其对 ACS 中病理生理机制和心血管血液动力学的影响，并根据文献，总结了迄今为止关于这一主题的所有现有证据。这些数据在很大程度上指出，ACS 中三碘甲状腺原氨酸（T3）水平降低可能有助于预测 ACS 的结局。
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