Department of Paediatric Endocrinology, Evelina London Children's Hospital, London, UK.
Department of Paediatric Metabolic Bone Disease, Sheffield Children's Hospital NHS Foundation Trust, Sheffield, UK.
J Pediatr Endocrinol Metab. 2021 Apr 16;34(8):1055-1060. doi: 10.1515/jpem-2020-0580. Print 2021 Aug 26.
Nutritional rickets may be a preventable cause of craniosynostosis. This potential association is under-recognised. A late diagnosis of craniosynostosis may result in reduced brain growth, raised intracranial pressure and long-term psychosocial problems.
We present four cases of craniosynostosis associated with nutritional rickets. Those who had delayed presentation underwent emergency craniotomy.
Treatment of nutritional rickets and early identification of craniosynostosis can reduce morbidity in these children.
营养性佝偻病可能是颅缝早闭的一个可预防病因。这种潜在的关联尚未被充分认识。颅缝早闭的诊断较晚可能导致脑生长受限、颅内压升高和长期的社会心理问题。
我们报告了 4 例与营养性佝偻病相关的颅缝早闭病例。那些有延迟表现的患儿接受了紧急开颅手术。
治疗营养性佝偻病并早期识别颅缝早闭可以降低这些患儿的发病率。
