Department of Radiology, Huzhou Maternity & Child Health Care Hospital, Huzhou, China.
Department of Children's Health, Huzhou Maternity & Child Health Care Hospital, Huzhou, China.
J Matern Fetal Neonatal Med. 2022 Dec;35(25):6229-6235. doi: 10.1080/14767058.2021.1910657. Epub 2021 Apr 18.
To investigate the relationship of mild-to-moderate simple bilateral fetal ventriculomegaly with postnatal neurological development.
Cases of simple lateral ventricular dilatation (273) were divided into bilateral mild dilatation (10.0-12.0 mm, 62), bilateral moderate dilatation (12.1-15.0 mm, 29), unilateral mild dilatation (133), and unilateral moderate dilatation (49) groups. The control group comprised 50 normal fetuses. Neurological development was assessed using Gesell Developmental Schedules (GDS) at postnatal 3, 6, 12, and 18 months.
At postnatal 6, 12, and 18 months, the GDS score was higher for bilateral than for unilateral dilatation ( < .05). At postnatal 3 and 6 months, the GDS score was higher for the bilateral dilatation groups than for the control group ( < .05). At postnatal 6, 12, and 18 months, the GDS score was higher for the bilateral moderate dilatation group than for the unilateral moderate dilatation group ( < .05). Further, at postnatal 3, 6, 12, and 18 months, the GDS score was higher for the bilateral moderate dilatation group than for the control group ( < .05).
At postnatal month 6, the GDS evaluation results of the bilateral dilatation groups were significantly inferior compared to those of the unilateral dilatation group.
探讨轻度至中度单纯双侧胎儿脑室扩大与产后神经发育的关系。
将单纯侧脑室扩张(273 例)分为双侧轻度扩张(10.0-12.0mm,62 例)、双侧中度扩张(12.1-15.0mm,29 例)、单侧轻度扩张(133 例)和单侧中度扩张(49 例)组。对照组为 50 例正常胎儿。采用盖塞尔发育量表(GDS)在产后 3、6、12 和 18 个月评估神经发育情况。
产后 6、12 和 18 个月时,双侧扩张组的 GDS 评分均高于单侧扩张组(<0.05)。产后 3 和 6 个月时,双侧扩张组的 GDS 评分均高于对照组(<0.05)。产后 6、12 和 18 个月时,双侧中度扩张组的 GDS 评分均高于单侧中度扩张组(<0.05)。此外,产后 3、6、12 和 18 个月时,双侧中度扩张组的 GDS 评分均高于对照组(<0.05)。
产后 6 个月时,双侧扩张组的 GDS 评估结果明显差于单侧扩张组。