Department of Ultrasound, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
Department of Ultrasound, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Clin Hemorheol Microcirc. 2021;78(4):429-437. doi: 10.3233/CH-211164.
The contrast-enhanced ultrasound (CEUS) liver imaging reporting and data system (LI-RADS) is a relative new algorithm for hepatocellular carcinoma (HCC) assessment.
To validate the diagnostic efficiency of the intravascular perfusion based CEUS LI-RADS for HCC.
Archives of 873 patients with focal liver lesions (FLLs) undergoing CEUS were reviewed, and target images were read by two sonologists independently according to the CEUS LI-RADS. The diagnostic performance was calculated and compared.
Assessment with reference to CEUS LI-RADS, 87 of 218 FLLs (39.9%) were categorized as LR-5, 131 of 218 FLLs (60.1%) were categorized as non-LR-5, 19 of 99 HCCs were categorized as non-LR-5, and 7 of 119 non-HCCs were categorized as LR-5. The sensitivity, specificity, AUROC, positive and negative predictive values of CEUS LI-RADS for diagnosing HCC were 80.81%(95%CI: 71.7%-88.0%), 94.1%(95%CI: 88.3%-97.6%), 0.87 (95%CI: 0.82-0.92), 91.9%(95%CI: 84.1%-96.7%), and 85.5%(95%CI: 78.3%-91.0%), respectively.
The diagnostic efficiency of the intravascular perfusion based CEUS LI-RADS for the evaluation of HCCs is very good.
对比增强超声（CEUS）肝脏影像报告和数据系统（LI-RADS）是一种用于肝细胞癌（HCC）评估的相对较新的算法。
验证基于血管内灌注的 CEUS LI-RADS 对 HCC 的诊断效能。
回顾分析了 873 例接受 CEUS 检查的局灶性肝脏病变（FLL）患者的档案，由两名超声医师独立根据 CEUS LI-RADS 阅读靶图像。计算并比较了诊断性能。
参照 CEUS LI-RADS 评估，218 个 FLL 中有 87 个（39.9%）被归类为 LR-5，218 个 FLL 中有 131 个（60.1%）被归类为非 LR-5，99 个 HCC 中有 19 个（19.2%）被归类为非 LR-5，119 个非 HCC 中有 7 个（6.7%）被归类为 LR-5。CEUS LI-RADS 诊断 HCC 的敏感性、特异性、AUROC、阳性和阴性预测值分别为 80.81%（95%CI：71.7%-88.0%）、94.1%（95%CI：88.3%-97.6%）、0.87（95%CI：0.82-0.92）、91.9%（95%CI：84.1%-96.7%）和 85.5%（95%CI：78.3%-91.0%）。
基于血管内灌注的 CEUS LI-RADS 对 HCC 的评估具有很好的诊断效率。
