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厌食症患者的胃食管静脉曲张和肝脏增生性结节。

Gastroesophageal Varices and Hyperplastic Nodules of the Liver in a Patient with Anorexia Nervosa.

机构信息

Department of Gastroenterology and Medicine, Fukuoka University Faculty of Medicine, Japan.

Department of Pathology, Fukuoka University Faculty of Medicine, Japan.

出版信息

Intern Med. 2021 Oct 1;60(19):3107-3112. doi: 10.2169/internalmedicine.6855-20. Epub 2021 Apr 19.

DOI:10.2169/internalmedicine.6855-20
PMID:33867388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8545646/
Abstract

We report a case of anorexia nervosa (AN) with gastroesophageal varices (GEV) in a 36-year-old woman. The patient presented to our hospital with progressive bloating due to severe ascites. She had no history of alcohol intake. Esophagogastroduodenoscopy and enhanced computed tomography revealed GEV and multiple hepatic nodules, respectively. The histological examination of a liver biopsy specimen revealed similar features to nonalcoholic fatty liver disease and showed hyperplastic nodules that were suspected to be related to the uneven distribution of portal blood flow in the liver. In conclusion, patients with long-term AN should undergo abdominal imaging to detect signs of portal hypertension.

摘要

我们报告了一例 36 岁女性神经性厌食症（AN）合并胃食管静脉曲张（GEV）的病例。该患者因严重腹水逐渐出现腹胀，就诊于我院。患者无饮酒史。食管胃十二指肠镜和增强 CT 分别显示 GEV 和多个肝结节。肝脏活检组织的组织学检查显示出类似于非酒精性脂肪性肝病的特征，并显示出增生性结节，这些结节被怀疑与肝脏门静脉血流分布不均匀有关。总之，长期患有 AN 的患者应进行腹部影像学检查以检测门脉高压的迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75b4/8545646/3766dd935bd4/1349-7235-60-3107-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75b4/8545646/59ee39da43f7/1349-7235-60-3107-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75b4/8545646/8ff56eb9ee72/1349-7235-60-3107-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75b4/8545646/3766dd935bd4/1349-7235-60-3107-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75b4/8545646/59ee39da43f7/1349-7235-60-3107-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75b4/8545646/8ff56eb9ee72/1349-7235-60-3107-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75b4/8545646/3766dd935bd4/1349-7235-60-3107-g003.jpg

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2
Portal hypertension in prolonged anorexia nervosa with laxative abuse: a case report with liver and kidney biopsy data.长期神经性厌食症伴滥用泻药所致门静脉高压：一份伴有肝脏和肾脏活检数据的病例报告
Eat Weight Disord. 2021 Mar;26(2):733-738. doi: 10.1007/s40519-020-00902-x. Epub 2020 Apr 27.
3
Doughnut-like hyperintense nodules on hepatobiliary phase without arterial-phase hyperenhancement in cirrhotic liver: imaging and clinicopathological features.
肝硬化肝脏肝胆期呈类甜甜圈样高信号结节，无动脉期强化：影像学和临床病理特征。
Eur Radiol. 2019 Dec;29(12):6489-6498. doi: 10.1007/s00330-019-06329-y. Epub 2019 Jul 5.
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Portal hypertension in prolonged anorexia nervosa with laxative abuse: A case report of three patients.长期神经性厌食伴滥用泻药致门静脉高压症三例报告
Int J Eat Disord. 2019 Feb;52(2):211-215. doi: 10.1002/eat.23007. Epub 2019 Jan 12.
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Hepatic Complications of Anorexia Nervosa.神经性厌食症的肝脏并发症
Dig Dis Sci. 2017 Nov;62(11):2977-2981. doi: 10.1007/s10620-017-4766-9. Epub 2017 Sep 20.
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Aggressive non-alcoholic steatohepatitis following rapid weight loss and/or malnutrition.快速减肥和/或营养不良后出现的侵袭性非酒精性脂肪性肝炎。
Mod Pathol. 2017 Jun;30(6):834-842. doi: 10.1038/modpathol.2017.13. Epub 2017 Mar 3.
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