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雷尼替丁召回事件的“灼伤”:当前的见解和缓解策略。

The 'burn' of ranitidine recall: current insights and mitigation strategies.

机构信息

Department of Gastroenterology and Hepatology, The University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Department of Medicine, The Wright Center for Graduate Medical Education, Scranton, Pennsylvania, USA.

出版信息

Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e1013-e1016. doi: 10.1097/MEG.0000000000002161.

Abstract

Ranitidine was one of the most commonly used medications for the treatment of gastroesophageal reflux disease. On 1 April 2020, the US Food and Drug Administration requested all manufacturers to immediately withdraw ranitidine from the market because of concern of higher than acceptable levels of N-nitrosodimethylamine, a potential carcinogen. Herein, we highlight the reason for this recall, along with the effects of this recall on both the patients and healthcare practitioners, and offer insights on management strategies.

摘要

雷尼替丁是治疗胃食管反流病最常用的药物之一。2020 年 4 月 1 日,美国食品药品监督管理局要求所有制造商立即将雷尼替丁从市场上撤回,因为担心其含量高于可接受水平的潜在致癌物 N-亚硝基二甲胺。在此,我们重点介绍此次召回的原因,以及此次召回对患者和医疗保健从业者的影响,并提供有关管理策略的见解。

相似文献

1
The 'burn' of ranitidine recall: current insights and mitigation strategies.雷尼替丁召回事件的“灼伤”:当前的见解和缓解策略。
Eur J Gastroenterol Hepatol. 2021 Dec 1;33(1S Suppl 1):e1013-e1016. doi: 10.1097/MEG.0000000000002161.
2
Medicine and Media: The Ranitidine Debate.医学与媒体:雷尼替丁之争。
Clin Transl Sci. 2020 Jul;13(4):649-651. doi: 10.1111/cts.12753. Epub 2020 Feb 27.

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