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膀胱内卡介苗治疗后粟粒性肺结核:一种常见治疗方法的罕见并发症。

Miliary tuberculosis following intravesical Bacillus Calmette and Guérin therapy: A rare complication of a frequent procedure.

作者信息

Loued Lobna, Fahem Nesrine, Kaddoussi Rania, Abdelaaly Mabrouk, Cheikh Mhamed Saoussen, Rouatbi Naceur

机构信息

Pneumology Department, Fattouma Bourguiba Hospital of Monastir, Tunisia.

Radiology Department, Fattouma Bourguiba Hospital of Monastir, Tunisia.

出版信息

Urol Case Rep. 2021 Mar 26;38:101655. doi: 10.1016/j.eucr.2021.101655. eCollection 2021 Sep.

Abstract

The standard treatment for superficial vesical tumors is transurethral resection (TUR) followed by intravesical instillation of Bacillus Calmette and Guérin (BCG). Pulmonary complications of BCG-therapy are rare but could be life threatening. We report the case of a 54-year-old patient who received BCG-therapy after TUR. After the sixth session of BCG instillations, the patient was diagnosed with a miliary tuberculosis secondary to BCG-therapy. We observed a progressive clinical and radiological improvement under specific tuberculosis treatment. Early diagnosis of pulmonary side effects of BCG-therapy and prompt treatment are the keys to complete recovery and survival.

摘要

浅表性膀胱肿瘤的标准治疗方法是经尿道切除术(TUR),然后膀胱内灌注卡介苗(BCG)。卡介苗治疗的肺部并发症很少见,但可能危及生命。我们报告一例54岁患者,在经尿道切除术后接受卡介苗治疗。在卡介苗灌注第六次后,该患者被诊断为卡介苗治疗继发的粟粒性肺结核。在特定的抗结核治疗下,我们观察到临床和影像学表现逐渐改善。早期诊断卡介苗治疗的肺部副作用并及时治疗是完全康复和生存的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16a/8040259/2881dad29578/gr1.jpg

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