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Histone-DNA Complexes and Coagulation after Intracerebral and Subarachnoid Hemorrhage.

作者信息

Gyldenholm Tua, Hvas Anne-Mette, Lauridsen Signe V, Sandgaard Emilie, Hvas Christine L

机构信息

Thrombosis and Hemostasis Research Unit, Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.

Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

出版信息

TH Open. 2021 Apr 14;5(2):e139-e142. doi: 10.1055/s-0041-1728672. eCollection 2021 Apr.

DOI:10.1055/s-0041-1728672
PMID:33870078
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8046511/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/459a/8046511/3eb19f5d44aa/10-1055-s-0041-1728672-i200097-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/459a/8046511/3eb19f5d44aa/10-1055-s-0041-1728672-i200097-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/459a/8046511/3eb19f5d44aa/10-1055-s-0041-1728672-i200097-1.jpg

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本文引用的文献

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Thromboelastometry Shows Early Hypercoagulation in Patients with Spontaneous Subarachnoid Hemorrhage.血栓弹力描记术显示自发性蛛网膜下腔出血患者早期存在高凝状态。
World Neurosurg. 2019 Oct;130:e140-e149. doi: 10.1016/j.wneu.2019.06.019. Epub 2019 Jun 14.
2
Coagulation Profile after Spontaneous Intracerebral Hemorrhage: A Cohort Study.自发性脑出血后的凝血指标：一项队列研究。
J Stroke Cerebrovasc Dis. 2018 Nov;27(11):2951-2961. doi: 10.1016/j.jstrokecerebrovasdis.2018.06.022. Epub 2018 Jul 30.
3
The effect of fresh frozen plasma in critically ill patients.
新鲜冰冻血浆对重症患者的影响。
Acta Anaesthesiol Scand. 2017 May;61(5):492-501. doi: 10.1111/aas.12885.
4
Post-cardiac arrest level of free-plasma DNA and DNA-histone complexes.心脏骤停后游离血浆DNA及DNA-组蛋白复合物水平
Acta Anaesthesiol Scand. 2017 May;61(5):523-531. doi: 10.1111/aas.12882. Epub 2017 Mar 23.
5
Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients.细胞外组蛋白H3水平与抗凝血酶水平及血小板计数呈负相关，并与脓毒症患者的死亡率相关。
Thromb Res. 2015 Sep;136(3):542-7. doi: 10.1016/j.thromres.2015.06.035. Epub 2015 Jul 23.
6
Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation.血浆组蛋白在人类脓毒症中的作用及其对细胞损伤和炎症的影响。
Crit Care. 2014 Sep 24;18(5):543. doi: 10.1186/s13054-014-0543-8.
7
Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism.重组血栓调节蛋白可保护小鼠免于组蛋白诱导的致命性血栓栓塞。
PLoS One. 2013 Sep 30;8(9):e75961. doi: 10.1371/journal.pone.0075961. eCollection 2013.
8
Blood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after trauma.创伤后早期，组蛋白复合DNA片段的血液水平与凝血病、炎症及内皮损伤相关。
J Emerg Trauma Shock. 2013 Jul;6(3):171-5. doi: 10.4103/0974-2700.115327.
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Extracellular histone release in response to traumatic injury: implications for a compensatory role of activated protein C.细胞外组蛋白释放对创伤性损伤的反应：激活蛋白 C 补偿作用的意义。
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J Thromb Haemost. 2011 Sep;9(9):1795-803. doi: 10.1111/j.1538-7836.2011.04422.x.