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经鼻高流量湿化氧疗在治疗 COVID-19 合并呼吸衰竭患者中的应用:六例患者的良好结局报告

Continuous positive airway pressure in the treatment of COVID-19 patients with respiratory failure. A report of six cases with excellent outcome.

机构信息

Department of Internal Medicine, University Hospital of Patras, Rion, Greece.

Intensive Care Unit, University Hospital of Patras, Rion, Greece.

出版信息

Adv Respir Med. 2021;89(2):197-202. doi: 10.5603/ARM.a2020.0181. Epub 2021 Apr 19.

DOI:10.5603/ARM.a2020.0181
PMID:33871045
Abstract

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently considered a significant threat to global health and global economy. This new rapidly spreading virus causes enormous stress to healthcare systems as large number of patients present with respiratory failure, needing intubation and mechanical ventilation. While the industry is racing to meet the rising demand for ventilators, all the alternative respiratory support modalities are employed to save lives in hospitals around the globe. We hereby report 6 patients who were diagnosed with SARS-CoV-2 and treated with continuous positive airway pressure in a negative pressure isolated room in a tertiary center in western Greece. The rapid progression of mild flu-like symptoms to respiratory failure in all patients was controlled with the use of continuous positive airway pressure making this strategy a reasonable alternative to respiratory failure due to SARS-CoV-2 as it may avert intubation and mechanical ventilation.

摘要

由严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)引起的 2019 年冠状病毒病(COVID-19)目前被认为是对全球健康和全球经济的重大威胁。这种新的迅速传播的病毒给医疗保健系统带来了巨大压力,因为大量患者出现呼吸衰竭,需要插管和机械通气。虽然该行业正在竞相满足呼吸机需求的增长,但在全球范围内的医院中,所有其他替代呼吸支持方式都被用来拯救生命。在此,我们报告了 6 例在希腊西部一家三级中心的负压隔离病房中使用持续气道正压通气治疗的 SARS-CoV-2 感染患者。所有患者的轻度流感样症状迅速进展为呼吸衰竭,均通过持续气道正压通气得到控制,因此,对于因 SARS-CoV-2 引起的呼吸衰竭,这种策略是一种合理的替代方法,因为它可能避免插管和机械通气。

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