Department of Neurosurgery, Houston Methodist Hospital Neurological Institute, Houston, Texas, USA.
Department of Neurosurgery, Houston Methodist Hospital Neurological Institute, Houston, Texas, USA.
World Neurosurg. 2021 Jul;151:e308-e316. doi: 10.1016/j.wneu.2021.04.028. Epub 2021 Apr 16.
Recently, a hybrid anterior column realignment-pedicle subtraction osteotomy (ACR-PSO) approach has been conceived for patients with severe rigid sagittal deformity, the clinical and radiographic outcomes of which require further investigation compared with ACR only.
A single-center, retrospective chart review identified patients undergoing a combination of hyperlordotic lateral lumbar interbody grafting (ACR) and concurrent Schwab grade 3 three-column osteotomy and propensity-matched patients undergoing ACR only in the same time frame. Anterior longitudinal ligament was directly released or partially sectioned in all patients. Chart data included demographics, Oswestry Disability Index scores, ACR and osteotomy locations, cage dimensions, fusion length, and complications. Radiographic measurements included lumbar lordosis, sagittal vertical axis, pelvic tilt (PT), and proximal junctional kyphosis.
Fourteen patients were enrolled in the ACR + PSO group and 36 in the ACR-only group. Mean ages were 68.5 and 63.9 years, 64% and 67% were female, average body mass index was 27.9 and 29.2, and cardiopulmonary comorbidities were 21% and 17%, respectively. There was no difference in complications (P = 0.347). The average follow-up for the ACR + PSO and ACR-only groups were 22 and 18 months, respectively. Excluding 2 mortalities, fusion occurred in all patients. Average change in lumbar lordosis measured -40.8 ± 9.2 degrees and -19.1 ± 15.7 degrees (P = 0.0006), and PT correction measured 10.5 ± 3.4 degrees and 27.3 ± 1.6 degrees (P < 0.0001), respectively.
For patients with severe rigid sagittal deformity, the hybrid ACR-PSO approach offers significant restoration of lumbar lordosis compared with ACR only, with similar complications but reduced PT correction.
最近,一种混合前柱矫正-椎弓根切除截骨术(ACR-PSO)方法被用于治疗严重僵硬的矢状面畸形患者,与单纯 ACR 相比,其临床和影像学结果需要进一步研究。
单中心回顾性病历分析,纳入在同一时期接受过 ACR 联合 Schwab 3 级三柱截骨术的患者(ACR+PSO 组)和仅接受 ACR 的患者(ACR 组)。所有患者均直接或部分松解前纵韧带。病历数据包括患者人口统计学特征、Oswestry 功能障碍指数评分、ACR 和截骨位置、椎间融合器尺寸、融合长度和并发症等。影像学测量包括腰椎前凸角、矢状面垂直轴、骨盆倾斜角(PT)和近端交界性后凸角。
共纳入 14 例 ACR+PSO 组患者和 36 例 ACR 组患者。ACR+PSO 组患者的平均年龄为 68.5 岁,64%为女性,平均 BMI 为 27.9,心肺合并症为 21%;ACR 组患者的平均年龄为 63.9 岁,67%为女性,平均 BMI 为 29.2,心肺合并症为 17%。两组患者并发症发生率无差异(P=0.347)。ACR+PSO 组和 ACR 组的平均随访时间分别为 22 个月和 18 个月。除 2 例死亡外,所有患者均融合。腰椎前凸角平均改善-40.8°±9.2°,-19.1°±15.7°(P=0.0006);PT 平均矫正 10.5°±3.4°,27.3°±1.6°(P<0.0001)。
对于严重僵硬的矢状面畸形患者,与单纯 ACR 相比,混合 ACR-PSO 方法可显著恢复腰椎前凸角,并发症相似,但 PT 矫正减少。