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对于颅内动脉瘤的栓塞治疗,小圈是否比大圈作为收尾圈更有效?使用 GALAXY G3™ MINI 微圈作为收尾圈在单中心的结果。

Is a small coil more effective as a finishing coil for the embolization of intracranial aneurysms? Outcomes using GALAXY G3™ MINI micro-coils as finishing coils in a single center.

机构信息

Department of Neurosurgery, Myong-Ji St. Mary's Hospital, Seoul, South Korea.

Department of Emergency Medicine, Myong-Ji St. Mary's Hospital, Seoul, South Korea.

出版信息

Interv Neuroradiol. 2021 Dec;27(6):798-804. doi: 10.1177/15910199211011858. Epub 2021 Apr 19.

DOI:10.1177/15910199211011858
PMID:33874767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8673902/
Abstract

OBJECTIVE

The purpose of this study was to compare the outcomes of coil embolization using a 0.009 inches primary outer diameter coil as finishing coil (FC) to that of 0.01 inches.

METHODS

From February and August 2020, 131 aneurysms that performed coil embolization using FC with a second loop diameter of 1 mm, were reviewed retrospectively, conducting propensity score matching and logistic regression analysis. Angiographic results such as, occlusion grade, packing density, failure and event were compared between 0.009 inches coil of GALAXY G3™ MINI microcoil (n = 54) and 0.01 inches coils (n = 77).

RESULTS

There were no statistically significant differences between two groups, but more events occurred in the 0.009 group. (Odds ratio, 3.65; 95% CI, 1.06-12.55; P = 0.031) In the results of coil embolization, successful occlusion occlusion (complete occlusion and residual neck) was identified more in the 0.01 group. After propensity score matching, the variables in each group were similar, but the successful occlusion was higher in the 0.01 group as in the total population. Events tended to occur more frequently in the 0.009 inch group, and logistic regression analysis showed slightly higher events in the angled microcatheter. (48.3% versus 76.9%., P = 0.075), Also, the 0.009 inch FC is an independent risk factor. (Odds ratio, 3.84; 95% CI, 1.07-13.80; P = 0.039).

CONCLUSIONS

Using 0.01 inches coils as FC increased the packing density after the procedure, and showed more successful occlusion than using a 0.009 inches coil. The probability of unexpected events was observed more than three times in the 0.009 inch group.

摘要

目的

本研究旨在比较使用 0.009 英寸初级外径圈作为收尾圈(FC)的线圈栓塞治疗结果与 0.01 英寸的结果。

方法

回顾性分析 2020 年 2 月至 8 月期间采用 FC 进行的 131 例动脉瘤栓塞治疗患者的临床资料,采用倾向性评分匹配和逻辑回归分析。比较 0.009 英寸 GALAXY G3™MINI 微线圈(n=54)和 0.01 英寸线圈(n=77)的血管造影结果,如闭塞程度、填塞密度、失败和事件等。

结果

两组间无统计学差异,但 0.009 组事件发生率更高。(比值比,3.65;95%置信区间,1.06-12.55;P=0.031)在栓塞结果中,0.01 组更易实现完全闭塞(完全闭塞和残余颈部)。在倾向评分匹配后,各组间变量相似,但在总人群中,0.01 组的完全闭塞率更高。0.009 英寸组的事件发生率更高,逻辑回归分析显示,使用角度微导管的事件发生率略高。(48.3%比 76.9%,P=0.075),同时,0.009 英寸 FC 是独立的危险因素。(比值比,3.84;95%置信区间,1.07-13.80;P=0.039)。

结论

使用 0.01 英寸的线圈作为 FC 可以增加术后的填塞密度,与使用 0.009 英寸的线圈相比,显示出更高的闭塞成功率。在 0.009 英寸组中观察到意外事件的概率是 0.01 英寸组的三倍多。

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