Kinsley C, Svare B
Department of Psychology, State University of New York, Albany 12222.
Physiol Behav. 1988;42(1):7-13. doi: 10.1016/0031-9384(88)90252-1.
Prenatal stress (heat and restraint) reduced pregnancy-induced and elevated postpartum aggression in Rockland-Swiss (R-S) albino female mice. Though prenatally-stressed females were indistinguishable from control animals with respect to parental behavior during the virgin state, the former displayed slightly lower levels of nestbuilding during early pregnancy, and delivered slightly more male offspring at parturition. The young born to prenatally-stressed females exhibited deficits in birth weights and body weight gain in contrast to pups delivered by control females. The anogenital distances of prenatally-stressed females were shorter than those of control females, suggesting that alterations in fetal testosterone exposure may be responsible for disruptions in behavior and reproduction.
产前应激（高温和束缚）降低了罗克兰-瑞士（R-S）白化雌性小鼠孕期诱发的攻击性，并增强了产后的攻击性。虽然产前应激的雌性小鼠在未生育状态下的母性行为与对照动物没有区别，但前者在怀孕早期筑巢水平略低，分娩时雄性后代略多。与对照雌性所生幼崽相比，产前应激雌性所生幼崽出生体重和体重增加存在缺陷。产前应激雌性的肛门生殖器距离比对照雌性短，这表明胎儿睾酮暴露的改变可能是行为和生殖紊乱的原因。
