MS can be considered a primary progressive disease in all cases, but some patients have superimposed relapses - Yes.
作者信息
Scalfari Antonio
机构信息
Centre of Neuroscience, Department of Medicine, Imperial College London, Charing Cross Hospital, London, UK.
出版信息
Mult Scler. 2021 Jun;27(7):1002-1004. doi: 10.1177/13524585211001789. Epub 2021 Apr 20.
Abstract
摘要
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MS can be considered a primary progressive disease in all cases, but some patients have superimposed relapses - Yes.在所有病例中，多发性硬化症都可被视为一种原发性进行性疾病，但有些患者会出现叠加性复发——是的。
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MS can be considered a primary progressive disease in all cases, but some patients have superimposed relapses - No.在所有病例中，多发性硬化症都可被视为一种原发性进行性疾病，但有些患者会出现叠加性复发——不对。
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Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials.在两项随机临床试验的汇总分析中，复发无关进展与复发相关恶化对典型复发型多发性硬化症总体确认残疾累积的贡献。
JAMA Neurol. 2020 Sep 1;77(9):1132-1140. doi: 10.1001/jamaneurol.2020.1568.
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Interplay Between Age and Neuroinflammation in Multiple Sclerosis: Effects on Motor and Cognitive Functions.年龄与多发性硬化症神经炎症之间的相互作用：对运动和认知功能的影响
Front Aging Neurosci. 2018 Aug 8;10:238. doi: 10.3389/fnagi.2018.00238. eCollection 2018.
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Defining secondary progressive multiple sclerosis.定义继发进展型多发性硬化症。
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The relationship of age with the clinical phenotype in multiple sclerosis.多发性硬化症的临床表型与年龄的关系。
Mult Scler. 2016 Nov;22(13):1750-1758. doi: 10.1177/1352458516630396. Epub 2016 Feb 11.
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Primary Progressive Multiple Sclerosis Evolving From Radiologically Isolated Syndrome.原发性进行性多发性硬化症由放射孤立综合征演变而来。
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Progressive multiple sclerosis: pathology and pathogenesis.进行性多发性硬化症：病理学与发病机制。
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Natural history of multiple sclerosis: a unifying concept.多发性硬化症的自然史：一个统一的概念。
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