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[评估骨闪烁显像临床疗效的前瞻性研究——受试者工作特征分析]

[Prospective study to assess the clinical efficacy of bone scintigraphy--ROC analysis].

作者信息

Akiyama Y, Yui N, Matsumoto T, Iinuma T, Ishikawa T, Nakajima T, Machida K, Nishikawa J, Iio M, Uno K

机构信息

Chiba Cancer Center Hospital.

出版信息

Radioisotopes. 1988 Mar;37(3):148-54. doi: 10.3769/radioisotopes.37.3_148.

Abstract

The value of preoperative bone scans in patients with primaly breast and prostate cancer was evaluated prospectively. The methodology and some clinical results were described previously. The clinical efficacy of the bone scan was assessed by using ROC analysis and we obtained the following results. 1) Preoperative bone scan of carcinomas of the breast is effective for patients with clinical stage IIIA, IIIB and IV. It is not so effective for patients with clinical stage I and II, but there is no denying the importance of it, because it provides a base-line scan for comparison to subsequent scans obtained in the postoperative period. 2) Preoperative bone scan of prostate carcinomas is effective, especially for clavicle, the ribs and the cervical spine, when compared with bone X-ray. 3) Bone scan is effective means for patients who were diagnosed uncertainly to have bone metastasis.

摘要

对原发性乳腺癌和前列腺癌患者术前骨扫描的价值进行了前瞻性评估。该方法和一些临床结果已在之前进行了描述。通过受试者工作特征(ROC)分析评估骨扫描的临床疗效,我们得到了以下结果。1)乳腺癌术前骨扫描对临床分期为IIIA、IIIB和IV期的患者有效。对临床I期和II期患者效果不佳,但不可否认其重要性,因为它为术后获得的后续扫描提供了基线扫描以便比较。2)与骨X线相比,前列腺癌术前骨扫描有效,尤其是对锁骨、肋骨和颈椎。3)对于诊断不确定是否有骨转移的患者,骨扫描是一种有效的手段。

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