Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Department of Anaesthesiology & Intensive Care Medicine, Haukeland University Hospital, Bergen, Norway.
Future Cardiol. 2021 Nov;17(8):1321-1326. doi: 10.2217/fca-2020-0235. Epub 2021 Apr 20.
COVID-19 infection primarily causes severe pneumonia complicated by acute respiratory distress syndrome and multiorgan failure requiring a ventilator support. We present a case of a 55-year-old male, admitted with COVID-19. He was obese but had no other medical conditions. His blood pressure was measured by his general physician on several occasions in the past, all values being normal (<140/90 mmHg). He developed multiorgan failure, requiring vasopressor and ventilator support for 17 days. A prone positioning improved the arterial oxygenation, and reduced the need for supplemental oxygen. After recovery, he showed persistently elevated blood pressure and sinus tachycardia both in clinic and out-of-clinic. The activation of the renin-angiotensin-aldosterone and sympathetic systems, volume-overload, hyperreninemia and cytokine storm might have contributed to the exaggerated cardiovascular response.
新型冠状病毒肺炎（COVID-19）主要引起严重肺炎，并发急性呼吸窘迫综合征和多器官衰竭，需要呼吸机支持。我们报告了一例 55 岁男性 COVID-19 患者。他肥胖，但无其他疾病。他的血压曾由全科医生多次测量，均正常（<140/90mmHg）。他发生多器官衰竭，需要血管加压药和呼吸机支持 17 天。俯卧位改善了动脉氧合，减少了对补充氧气的需求。恢复后，他在诊所和诊所外都表现出持续升高的血压和窦性心动过速。肾素-血管紧张素-醛固酮和交感神经系统的激活、容量超负荷、高肾素血症和细胞因子风暴可能导致心血管反应过度。
