Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC.
Groupe de recherche interdisciplinaire sur les maladies neuromusculaires, CIUSSS Saguenay-Lac-St-Jean/Neuromuscular Clinic, Saguenay, QC.
Can J Diet Pract Res. 2021 Jun 1;82(2):95-97. doi: 10.3148/cjdpr-2021-003. Epub 2021 Apr 20.
To document the nutritional risk in adults with oculopharyngeal muscular dystrophy (OPMD) and its association with oropharyngeal dysphagia. In this cross-sectional study, 33 adults with molecular confirmation of OPMD between 50 and 75 years old were recruited from the registry of a university-affiliated neuromuscular clinic. Nutritional risk was assessed with the French version of Seniors in the Community: Risk Evaluation for Eating and Nutrition II (SCREEN II), whereas the severity of dysphagia was assessed using the French-Canadian version of the Sydney Swallow Questionnaire. Anthropometric measurements were performed with standardized procedures. SCREEN II scores showed high nutritional risk for 81.8% of OPMD participants with 6 factors contributing to nutritional risk in at least 50% of the sample. Pearson's correlational analysis showed a significant moderate relationship between dysphagia and nutritional risk ( = -0.470; = 0.006). To our knowledge, this study is the first to investigate the nutritional risk of adults with OPMD. Our results indicate that individuals with OPMD may be at high nutritional risk mostly associated with swallowing difficulty, in the absence of a low body mass index. The present study highlights the need for dietary counseling in OPMD.
为了记录眼咽型肌营养不良症（OPMD）成人的营养风险，并研究其与口咽性吞咽困难的关系。在这项横断面研究中，我们从一所大学附属医院的神经肌肉诊所的登记处招募了 33 名年龄在 50 至 75 岁之间、分子确诊为 OPMD 的成年人。使用老年人社区：营养评估和饮食 II （SCREEN II）的法语版评估营养风险，使用加拿大法语版的悉尼吞咽问卷评估吞咽困难的严重程度。采用标准化程序进行人体测量。SCREEN II 评分显示，81.8%的 OPMD 参与者存在高营养风险，有 6 个因素至少在 50%的样本中导致营养风险。Pearson 相关分析显示，吞咽困难与营养风险之间存在显著的中度关系（ = -0.470； = 0.006）。据我们所知，这项研究首次调查了 OPMD 成人的营养风险。我们的研究结果表明，OPMD 患者可能存在较高的营养风险，主要与吞咽困难有关，而不是与低体重指数有关。本研究强调了在 OPMD 中需要进行饮食咨询。
