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一种减少心电图诊断系统误报的新方法:噪声信号的捕获与量化。

A novel method to reduce false alarms in ECG diagnostic systems: capture and quantification of noisy signals.

作者信息

Zhu Wenliang, Qiu Lishen, Cai Wenqiang, Yu Jie, Li Deyin, Li Wanyue, Zhong Jun, Wang Yan, Wang Lirong

机构信息

School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, People's Republic of China.

Suzhou Institute of Biomedical Engineering and Technology, China Academy of Sciences, People's Republic of China.

出版信息

Physiol Meas. 2021 Jul 28;42(7). doi: 10.1088/1361-6579/abf9f4.

Abstract

. Muscle artifacts (MA) and electrode motion artifacts (EMA) in electrocardiogram (ECG) signals lead to a large number of false alarms from cardiac diagnostic systems. To reduce false alarms, it is necessary to improve the performance of the diagnostic algorithm in noisy environments by removing excessively noisy signals. However, existing methods focus on signal quality assessment and contain too many artificial features. Here, we present a novel method to flexibly eliminate noisy signals without any artificial features.. Our method contains an improved lightweight deep neural network (DNN) to capture the signal portions damaged by EMA and MA, uses the sample entropy to quantize noisy portions, and discards those portions that exceed a defined threshold. Our method was tested in conjunction with Pan-Tompkins (PT), Filter Bank (FB), and 'UNSW' R-peak detection algorithms along with two heartbeat classification algorithms on datasets synthesized from the MIT-BIH Noise Stress Test Database, the China Physiological Signal Challenge 2018 Database and the MIT-BIH Arrhythmia Database.. For PT R-peak detection algorithms, the sensitivity (Se) increased noticeably from 89.01% to 99.42% in the synthesized datasets with a signal-to-noise ratio of 6 dB. With the same datasets, the Se of the FB algorithm increased about 9.29%, and a 3.64% increase occurred in the Se of the 'UNSW' algorithm. For heartbeat classification algorithms, the overall F1-score increased about 6% in the synthesized one-heartbeat datasets. It is the first study to utilize a DNN to capture noisy segments of the ECG signal.. Too many false alarms can cause alarm fatigue. Our method can be utilized as the preprocessing before signal analysis, thereby reducing false alarms from the ECG diagnostic systems.

摘要

心电图(ECG)信号中的肌肉伪迹(MA)和电极运动伪迹(EMA)会导致心脏诊断系统产生大量误报。为了减少误报,有必要通过去除噪声过大的信号来提高诊断算法在噪声环境中的性能。然而,现有方法侧重于信号质量评估,且包含过多人工特征。在此,我们提出一种新颖的方法,可灵活消除噪声信号且不包含任何人工特征。我们的方法包含一个改进的轻量级深度神经网络(DNN),用于捕获受EMA和MA损坏的信号部分,使用样本熵对噪声部分进行量化,并丢弃那些超过定义阈值的部分。我们的方法与Pan - Tompkins(PT)、滤波器组(FB)和“新南威尔士大学(UNSW)”R波检测算法以及两种心跳分类算法一起,在由麻省理工学院 - 贝丝以色列女执事医疗中心噪声压力测试数据库、2018年中国生理信号挑战赛数据库和麻省理工学院 - 贝丝以色列女执事医疗中心心律失常数据库合成的数据集上进行了测试。对于PT R波检测算法,在信噪比为6 dB的合成数据集中,灵敏度(Se)从89.01%显著提高到99.42%。在相同的数据集中,FB算法的Se提高了约9.29%,“UNSW”算法的Se提高了3.64%。对于心跳分类算法,在合成的单心跳数据集中,总体F1分数提高了约6%。这是首次利用DNN捕获ECG信号噪声段的研究。过多的误报会导致警报疲劳。我们的方法可作为信号分析前的预处理,从而减少ECG诊断系统的误报。

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