Marinescu I, Tache A, Zimel A, Mogoş I
C. I. Parhon, Institute of Endocrinology, Bucharest, Romania.
Endocrinologie. 1988 Jan-Mar;26(1):59-63.
A 27-yr female patient was admitted to the hospital because of secondary amenorrhea and a severe and complex virilization syndrome. The urinary 17-Ks, 17 OHCS and testosterone glucuronide values were greatly increased. The plasma testosterone through very high, was within the normal limits in males (3.52 ng/ml). Urography, echography and CT scan revealed a large right adrenal tumor. Removal of the tumor brought about a considerable clinical improvement: reoccurrence of the menstrual cycle, a progressive decrease in the virilization syndrome and normalization of the urinary 17-Ks, 17-OHCS and of the plasma testosterone.
一名27岁女性患者因继发性闭经和严重复杂的男性化综合征入院。尿17-酮类固醇、17-羟皮质类固醇和睾酮葡萄糖醛酸苷值大幅升高。血浆睾酮水平虽极高，但在男性正常范围内（3.52纳克/毫升）。尿路造影、超声检查和CT扫描显示右侧肾上腺有一个大肿瘤。切除肿瘤后临床症状有明显改善：月经周期恢复，男性化综合征逐渐减轻，尿17-酮类固醇、17-羟皮质类固醇及血浆睾酮水平恢复正常。
